The most common cystic kidney disease causing renal failure in children is autosomal recessive polycystic kidney disease (ARPKD). ARPKD also affects the liver. These conditions often have extra-renal features which also need to be addressed. Until recently, treatments were mainly supportive but now ...
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Polycystic kidney disease (PKD) is a condition marked by the formation of cysts in the kidney. In some cases, the sac-like cysts can also be seen in the pancreas, liver, and spleen. It is one of the most common genetic disorders, running in the families and a common cause of kidney ...
The PKD Foundation is the only organization in the U.S. solely dedicated to finding treatments and a cure for polycystic kidney disease (PKD) and to improving the lives of those it affects. Since 1982, we have proudly funded more than 1,300 research projects and leveraged $1.5B in research...
Ensure that patients are aware that this disease is hereditary and that their children have a 50% chance of acquiring the disease. Patients should also understand that although several treatments are being tested, this disease currently has no cure. Only interventions that slow the progression of ...
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School of Basic Medical Sciences, Peking University, and Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China In polycystic kidney disease (PKD), a most common human genetic diseases, fluid-filled cysts displace normal renal tubules and cause end-stage rena...
Polycystic Kidney Disease (PKD) - Learn about the causes, symptoms, diagnosis & treatment from the Merck Manuals - Medical Consumer Version.
Chapman AB. Approaches to testing new treatments in autosomal dominant polycystic kidney disease: insights from the CRISP and HALT-PKD studies. Clin J Am Soc Nephrol CJASN. 2008;3(4):1197–204. ArticleCAS Kistler AD, Poster D, Krauer F, Weishaupt D, Raina S, Senn O, et al. Increases ...
Herein we review the current understanding of the pathophysiology of these conditions, as well as the current treatments derived from our understanding of the mechanisms of these diseases. Keywords: Polycystic kidney disease, autosomal dominant, recessive, end stage renal disease Introduction Polycystic ...