Main results The current review includes eight studies (22 papers), of which three studies are 4-6 weeks in duration and only one study is of more than 12 weeks' duration. Newer atypical drugs seemed to be broadly similar to clozapine using a clinical global index or trialists' definitions ...
Levels of olanzapine and clozapine, metabolized via the CYP1A2 pathway, may be decreased by cigarette smoking.71 Clinicians may notice a slightly decreased drug effect when patients are transitioned from a nonsmoking hospital unit to the outpatient setting. • Classifying antipsychotics into 2 distin...
Clozapine and oral contraceptives: a possible drug interaction. J Clin Psychopharmacol. 2002;22(6):621–2. Article CAS PubMed Google Scholar Haslemo T, Refsum H, Molden E. The effect of ethinylestradiol-containing contraceptives on the serum concentration of olanzapine and N-desmethyl olanzapine...
Bitter I, Czobor P, Dossenbach M, Volavka J (2005) Effectiveness of clozapine, olanzapine, quetiapine, risperidone, and haloperidol monotherapy in reducing hostile and aggressive behavior in outpatients treated for schizophrenia: a prospective naturalistic study (IC-SOHO). Eur Psychiatry 20:403–408...
heterogeneous effects of the different antipsychotics on cognitive domains; when compared to other antipsychotics, substances like amisulpride or quetiapine performed better on cognitive scores, yet other antipsychotics like haloperidol and clozapine lead to poorer performance [48]. In our study, we did ...
In one single study (n=228) amisulpiride seemed broadly similar to risperidone in most respects. There were no useful data presented relating to service use and costs. Very few data relating to quality of life were presented. Authors' conclusions The equivalence of clozapine and risperidone for ...
The proportion of treatment episodes that were at least 1-year long (conceptually similar to 1-year completer rates in RCTs) was 73.7% for clozapine, 57.6% for olanzapine, 52.0% for risperidone, 46.1% for quetiapine, 28.0% for ziprasidone, 30.9% for typicals of high-potency level, 43.6% ...
Glutamatergic neurometabolites in clozapine-responsive and -resistant schizophrenia. Int J Neuropsychopharmacol. 2015;18(6):pyu117. doi:10.1093/ijnp/pyu117 PubMedGoogle Scholar 58. Block W, Bayer TA, Tepest R, et al. Decreased frontal lobe ratio of N-acetyl aspartate to ...
People who are suffering from diagnosable mental conditions such as schizophrenia or paranoid personality disorder may benefit from the use of typical antipsychotic medications, such as chlorpromazine or haloperidol , or from the newer, atypical antipsychotic medications, such as clozapine , olanzapine , ...
Progressive subcortical volume loss in treatment-resistant schizophrenia patients after commencing clozapine treatment Article08 April 2020 Characteristics of gray matter alterations in never-treated and treated chronic schizophrenia patients ArticleOpen access12 May 2020 ...