Methyl-CpG-binding protein 2 (MeCP2) is an epigenetic regulator of gene expression that is essential for normal brain development. Mutations in MeCP2 lead to disrupted neuronal function and can cause Rett syndrome (RTT), a neurodevelopmental disorder. Previous studies reported cardiac dysfunction, ...
联系人:Dr.Xu, Biovector NTCC Inc. 电话:400-800-2947 工作QQ:1843439339 (微信同号) 邮件:Biovector@163.com 手机:18901268599 地址:北京 已注册 详细信息 咨询记录(共0条) Plasmid Name质粒名称:BioVector® pSBtet-Hyg-dCas9-KRAB-MeCP2_hU6-A10Gene/Insert插入基因名称: gRNA targeting Adam10 (Synthet...
While intron retention (IR) is considered a widely conserved and distinct mechanism of gene expression control, its regulation is poorly understood. Here we show that DNA methylation directly regulates IR. We also find reduced occupancy of MeCP2 near the
联系人:Dr.Xu, Biovector NTCC Inc. 电话:400-800-2947 工作QQ:1843439339 (微信同号) 邮件:Biovector@163.com 手机:18901268599 地址:北京 已注册 详细信息 咨询记录(共0条) Plasmid Name质粒名称: NAX_CAGGS_CAS9_m4_KRAB-MeCP2_EYFPGene/Insert插入基因名称: dCas9-KRAB-MeCP2 (Synthetic)Cat#货号: Bi...