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Mechanisms of resistance to antibacterial agents Bacteria may manifest resistance to antibacterial drugs through a variety of mechanisms. Some species of bacteria are innately resistant to ≥1 class of antimicrobial agents. In such cases, all strains of that bacterial species are likewise resistant to ...
The mechanisms of antimicrobial resistance in GNB may interfere with several facets of antibiotic stewardship algorithms in critically ill patients, including the choice of empirical regimen, available options for de-escalation, and the management of clinical failure due to the emergence of resistance und...
Mechanisms of emerging resistance associated with non-antibiotic antimicrobial agents: a state-of-the-art review Article 21 August 2023 Alternative therapeutic strategies to treat antibiotic-resistant pathogens Article 11 December 2023 ESKAPE pathogens: antimicrobial resistance, epidemiology, clinical impa...
Efflux pump-mediated resistance to new beta lactam antibiotics in multidrug-resistant gram-negative bacteria Article Open access 29 August 2024 References Walker, D. & Fowler, T. Annual Report of the Chief Medical Officer: Volume Two, 2011: Infections and the Rise of Antimicrobial Resistance (...
2. Antimicrobial Resistance Mechanisms of ESKAPE Pathogens Antimicrobial resistance genes may be carried on the bacterial chromosome, plasmid, or transposons [6]. Mechanisms of drug resistance fall into several broad categories, including drug inactivation/alteration, modification of drug binding sites/targe...
These drug resistance determinants are mediated via one of two distinct genetic mechanisms, a mutation in the bacterial chromosome or by a transmissible element; either a plasmid or a transposon. Significant differences exist between these two types of drug resistance as transmissible resistance, which...
Prevalence, Mechanisms and Dissemination of Antimicrobial Resistance in Enteric Foodborne Bacteria In this chapter, we have described the prevalence, specific mechanisms (based on the class of drugs) and dissemination of antimicrobial resistance in Campylobacter, Salmonella and E. coli. These three ...
The discovery of antimicrobial agents has saved the human race from a lot of sufferings due to the burden of these infectious diseases. Over the years, microorganisms have developed resistance to known antibiotics. Antimicrobial resistance among bacteria, viruses, parasites, and other disease-causing ...
One of the greatest threats to the survival of avian eggs is the risk of infection by microbes; as such, a large number of parental defense mechanisms have