Thrombosis: New mechanism of thrombus formation in CKDHoly et al . suggest that carbamylated (c)LDL promotes thrombus formation in patients with chronic kidney disease (CKD). They found that LDL isolated from these patients (CKD LDL) had higher levels of carbamylation than LDL from healthy ...
Inhibition of platelet-rich arterial thrombus in vivo: acute antithrombotic effect of intravenous HMG-CoA reductase therapy. OBJECTIVE: To test the hypothesis that statins will acutely inhibit platelet thrombus formation, intravenous lovastatin was assessed in our well-characteri... C Obi,W Wysokinski...
Journal of BiorheologyKaibara M. Rheological study on coagulation of blood with special reference to the triggering mechanism of venous thrombus formation. J Biorheol. 2009;23:2-10. doi:10.1007/s12573-009-0003-2.Kaibara, M., Rheological study on coagulation of blood with special reference to ...
2. This injury results in formation of a thrombus in the vessel without apparent intervention of perivascular, or extravascular, factors. 3. The thrombus grows by the adherence of white cells and platelets to the lesion over a period of hours. 4. Resolution of the lesion results from a ...
6 ear veins of the rest 3 rabbits as Health group weren't given any interventions, the veins were taken out to observe their morphology. Results: Comparison between Gelatum group and Gelatum heated group on vascular dilatation, Infiltration of inflammatory cell and Formation of thrombus had no ...
Aggregation of platelets via activated integrinαIIbβ3 is a prerequisite for thrombus formation. Phosphatidylserine-exposing platelets with a key role in the coagulation process disconnect from a thrombus by integrin inactivation via an unknown mechanism. Here we show that αIIbβ3 inactivation in ...
The central role of platelets in thrombus formation The pathophysiology of a thrombus includes atherosclerotic plaque rupture, platelet adhesion, activation, and aggregation leading to various degrees of thrombosis and occlusion, and ultimately, myocardial infarctionor stroke.3 ...
(defensins and S100 proteins) are involved in acute inflammatory response101,102,103. Under the action of IL-17A, endothelial cells can also release tissue factor and promote thrombus formation104. In the late stage of inflammation, IL-17A causes chronic inflammation by prolonging the survival ...
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally asymptomatic, it poses a significant threat to human life due to a high risk of rupture. Because of its strong concealment, it is difficult to diagnose the dis
The coagulation inhibition achieved with the HMP-modified sponge was comparable to traditional heparin administration in our in vivo model, but heparin can return to the body during auto-transfusion. Heparinized coatings, commonly used to reduce thrombus formation on blood-contacting devices59, rely on...