Oxidative stressReactive oxygen speciesAntioxidantDiseaseThe evolution of aerobic metabolic processes such as respiration unavoidably led to the production of reactive oxygen and nitrogen species (ROS and RNI) in mitochondria and peroxisomes of human. A common feature among the different ROS types is ...
Oxidative stress plays a critical role in AD and can even be considered a crucial central factor in the pathogenesis of AD. Previous reviews have also summarized the role of oxidative stress in AD, but these mainly review a specific signaling pathway. Taking oxidative stress as the central ...
These include: oxidative stress; excitotoxicity caused by aberrant glutamate signalling; mitochondrial dysfunction; disruption of the neurofilament network and intracellular trafficking along neurofilaments; aggregation of proteins; and involvement of non-neuronal cells in the vicinity of motor neurons. One ...
Multiple cancer therapies nowadays rely on oxidative stress to damage cancer cells. Here we investigated the biological and molecular effect of oxidative stress on the interaction between CD44 and hyaluronan (HA), as interrupting their binding can hinder cancer progression. Our experiments demonstrated th...
36 Indeed, PVIs are vulnerable to redox dysregulation/oxidative stress.37, 38, 39, 40 To examine the hypothesis that oxidative stress is part of a common pathway leading to PVI abnormalities, we performed a comparative immunohistological analysis of oxidative stress and PVIs in the anterior ...
CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells. Hepatic stellate cells (HSCs) are a major source of extracellular matrix, which, during fibrogenesis, undergo a process of "activation" characterized by in... N Nieto,SL Friedman,P Greenwel,... ...
induced overexpression of miR-25: the mechanism underlying the degeneration of melanocytes in vitiligo Q Shi1,2, W Zhang1,2, S Guo1,2, Z Jian1, S Li1, K Li1, R Ge1, W Dai1, G Wang1, T Gao1 and C Li*,1 Oxidative stress has a critical role in the pathogenesis of vitiligo....
5c, e). These results indicate that the targeting ability of C-dot SOD nanozymes to oxidation-damaged cells, which may be due to the better permeability of membrane damaged by oxidative stress, is consistent with the previous report that graphene-based nanoparticles target tumor cells by a cell...
Based on this, this paper introduced the generation of microbial oxidative stress under the stress of AgNPs, focusing on the influence mechanism of oxidative stress on microorganisms at the levels of cells, gene expression, transcriptome and proteome. This is helpful to further understand the role ...
aIdentification of model input parameters 式样输入参量的证明 [translate] aOxidative stress is another mechanism involving in the cataract development, which causes oxidation of lens protein. Decreased concentration of glutathione, ascorbate and antioxidant enzymes such as catalase, superoxide dismutase, ...