With the proliferation of synthetic drugs, research on the mechanism of action of addictive drugs and treatment methods is of great significance. Among them, methamphetamine (METH) is the most representative amphetamine synthetic drug, and the treatment of METH addiction has become an urgent medical ...
The purpose of this chapter is to review the evidence that substituted amphetamines (AMPHs), such as methamphetamine (METH), have neurotoxic potential, discuss critical determinants of AMPH neurotoxicity, and consider possible mechanisms underlying the neurotoxic action of AMPH and some of its ...
MA-induced analgesia was decreased by α-methyl-p-tyrosine (α-MT), 6-hydroxydopamine, diethyldithiocarbamate, disulfiram and reserpine, and increased by methamphetamine and norepinephrine (NE). The mode of action of MA was similar to that of Mor except for the results obtained upon combined ...
Fleckenstein AE, Volz TJ, Riddle EL, Gibb JW, Hanson GR: New insights into the mechanism of action of amphetamines. Annu Rev Pharmacol Toxicol. 2007;47:681-98. [Article] Haughey HM, Brown JM, Wilkins DG, Hanson GR, Fleckenstein AE: Differential effects of methamphetamine on Na(+)/Cl...
MA-induced analgesia was decreased by 伪-methyl-p-tyrosine (伪-MT), 6-hydroxydopamine, diethyldithiocarbamate, disulfiram and reserpine, and increased by methamphetamine and norepinephrine (NE). The mode of action of MA was similar to that of Mor except for the results obtained upon combined ...
1 Completed Not Available Methamphetamine Abuse / Methamphetamine Dependence / Substance Abuse 1 somestatus stop reason just information to hide 1 Completed Basic Science Acute Liver Injury, Drug Induced 1 somestatus stop reason just information to hide 1 Completed Other Respiratory Tract Disorders 1 so...
Studies were undertaken in mice and rats on the neurotoxic effects of methamphetamine on dopaminergic and 5-hydroxytryptaminergic neurones in the brain and... AR Green,RJD Souza,JL Williams,... - 《Neuropharmacology》 被引量: 141发表: 1992年 One-pot synthesis of homotryptamines from indoles Th...
The role of monoamines in the changes in body temperature induced by 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and its derivatives. Hyperthermia is probably the most widely known acute adverse event that can follow ingestion of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) by recrea......
Grasing K, Azevedo R, Karuppan S, Ghosh S (2001) Biphasic effects of selegiline on striatal dopamine: lack of effect on methamphetamine-induced dopamine depletion. Neurochem Res 26:65–74 Hu Y, Russek SJ (2008) BDNF and the diseased nervous system: a delicate balance between adaptive and pa...
2, 3 Completed Treatment Methamphetamine Dependence in Remission 1 somestatus stop reason just information to hide 2, 3 Recruiting Prevention Drug Induced Liver Injury / Hepatitis / Tuberculosis (TB) 1 somestatus stop reason just information to hide 2, 3 Recruiting Prevention Nephrotoxicity 1 somesta...