Schematic diagram illustrating the mechanism underlying the effect of salsalate and adiponectin on palmitate-induced insulin resistance.Tae, Woo JungHae, Yoon ChoiSo Young, LeeHo, Cheol HongSae, Jeong YangHye Jin, YooByungSoo, YounSei, Hyun Baik...
Which of the following hormone represent the mechanism of hormone acti... 02:27 Given below is a schematic representation of the mechanism of hormone ... 02:43 Explain the mechanism of hormone action. 02:49 The given diagram represents the mechasim of action for two categories... 06:42 De...
a: Venn diagram of intersecting targets of TMJOA and alpinumisoflavone; b: potential PPI protein interaction network for treating TMJOA with alpinumisoflavone; c: the PPI network diagram drawn by Cytoscape (the node area represents the target degree value, and the more important the target has the...
When there is inflammation, the intestinal microenvironment becomes extremely complicated, and many different types of cells release cytokines, such as interleukin (IL) and TNF, which can trigger inflammatory response via the action of complicated cellular subnets and accelerate, postpone, or even ...
and aVeendiagram was drawn as shown in Fig.1B. The specific intersection targets information were presented in Supplementary Table3. Component-target network diagram for a more comprehensive elucidation of the mechanism of action of ginseng in DM by Cytoscape 3.7.0. In Fig.1C, the blue diamond...
Fig.1 Schematic diagram of ferroptosis and iron lipid metabolism disorder 图1 铁死亡与铁脂代谢紊乱示意图 Full size|PPT slide 3 中药干预铁死亡的研究进展 3.1 中药通过调节铁死亡干预肿瘤 铁死亡在杀死和抑制癌细胞生长中起着至关重要的作用。中药抗肿瘤活性广泛,具有耐药性强、增效减毒和改善生活质量的特点,能...
A total of 376 potential DKD therapeutic targets were identified. The "composition-disease-target" network diagram implied that kaverol and astragaloside IV were the major active components of SP formula to play the therapeutic role of DKD. Its common pathways were correlated with the pathways of ...
Heat shock factor 1 (HSF1) is the critical orchestrator of cell responses to heat shock, and its dysfunction is linked to various diseases. HSF1 undergoes phase separation upon heat shock, and its activity is regulated by post-translational modifications
systems to improve the pharmacological activity of drugs with increasing pharmacokinetics (from drug absorption, continued distribution, metabolism, and excretion of the body), as well as changing the properties of drugs such as mechanism action, pharmacological reaction, and site-dependent a...
In conclusion, this study combines network pharmacology, molecular docking, molecular dynamic simulation, and animal experimental verification for the first time to study the effectiveness and mechanism of action of OA in the treatment of obesity. The findings reveal the potential of OA in the treatme...