In case of insulin, these advances have been mainly in the areas of insulin's second messenger and effects on membrane structure and function. For glucagon, effects on the enzyme systems are emphasized and, as for SRIF, it produces a wide variety of anti-secretory effects, including the ...
1981. Mechanism of action of insulin and insulin analogues: a comparison of the hepatic and peripheral effects on glucose turnover of insulin, proinsulin,... CV Tompkins,D Brandenburg,RH Jones,... - 《Diabetologia》 被引量: 19发表: 1981年 STUDIES ON THE MECHANISM OF SOMATOSTATIN ACTION ON ...
There are some phenomena to support our opinion that the field of insulin action is located intracellularly, and is concerned with energy generation, including mitochondria. In the experiments, the measurements of mitochondrial swelling were carried out by following the optical density of that suspension...
This chapter discusses the mechanisms of insulin action. It has been firmly established that in many mammalian cell systems, insulin, when added to intact cells, increases the transport of specific monosaccharides, amino acids, and electrolytes. Insulin binds to cells in which it enhances transport ...
Concerning the Mechanism of Insulin Action. Development of a cell-free ribosomal system, prepared from heart muscle of rats, has afforded the means for an analysis of the mechanism whereby insulin stimulates protein synthesis. The assay was carried out in circumstances where prote... IG Wool - ...
It provides a comprehensive view of the nature and mechanisms of action of these second messengers. Insulin has been one of the best studied mammalian proteins. After 1955, insulin became the first mammalian protein to be chemically synthesized. The molecular mechanisms underlying the multiple ...
Several new probes have become available that have shed some light on the problem of insulin action. These include cultured cell systems, which are highly responsive to insulin; new methods for studying receptor structure; mutant cell lines that possess defects in either the insulin receptor or ...
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat. Immunol. 12, 408–415 (2011). CAS PubMed PubMed Central Google Scholar Hotamisligil, G.S., Shargill, N.S. & Spiegelman, B.M. Adipose expression of tumor necrosis factor-alpha: direct role in ...
Interleukin (IL)-1β plays a role in insulin res... - 《Nature Immunology》 被引量: 1291发表: 2011年 Autoimmune T cell responses in the central nervous system Elsevier's Scopus, the largest abstract and citation database of peer-reviewed literature. Search and access research from the ...
A postulated mechanism for the insulin synergistic and insulin antagonistic action of growth hormone 来自 NCBI 喜欢 0 阅读量: 7 作者:RJ Mahler,O Szabo 摘要: Mahler RJ, Szabo O.DOI: 10.1016/B978-0-12-027361-4.50023-5 被引量: 9 年份: 1970 ...