Treatment success has been consistently lower than 60% and, prior to widespread introduction of new drugs, RR-TB resulted in a quarter million deaths annually. There is a clear need for more effective, safe, and well-tolerated drugs to support shorter and injection-free treatment regimens, ...
在主要收治来自于华东地区耐多药肺结核的上海肺科医院进行了一项临床研究,将具有一定适应症的难治性MDR/RR/XDR-TB患者进行前瞻性加回顾性队列研究,旨在探讨含Bdq方案在治疗难治性RR/MDR/XDR-TB中的贡献及及用药的安全性,并与接受...
Q8 – What is the most important class of drugs to treat MDR-TB? Name three that are effective.治疗MDR-TB的最重要的药物种类是什么?举出三个有效例子。相关知识点: 试题来源: 解析 2- The fluoroquinolones: Moxifloxacin, Gatifloxacin and Levofloxacin 氟喹诺酮类:莫西沙星(Moxifloxacin),加替沙星(...
Twitter Google Share on Facebook Dictionary Thesaurus Medical Encyclopedia AcronymDefinition MDR-TBMulti-Drug Resistant Tuberculosis Copyright 1988-2018AcronymFinder.com, All rights reserved. Suggest new definition Want to thank TFD for its existence?Tell a friend about us, add a link to this page, ...
Bedaquiline is the first anti-TB drug with a new mechanism of action to gain FDA approval in 40 years. As an ATP synthase inhibitor, bedaquiline depletes mycobacteria of their energy stores and can potentially remain active against TB, which often becomes resistant to older, bacteriostatic drugs...
We hypothesize that low-dose amikacin can be used as a safe and effective treatment for MDR-TB in situations where an adequate regimen cannot be constructed with Group A and B drugs, and where careful monitoring for adverse events is feasible. Keywords: Aminoglycosides, Therapeutic drug monitoring...
Corticosteroids (prednisolone and dexamethasone) are a class of HDT candidates which are already given to patients experiencing severe inflammation during anti-TB treatment. The drugs themselves do not have targeted effects but rather a general dampening of the host immune response to extend survival ...
n.Abbr.TB 1.An infectious disease of humans and animals caused by the tubercle bacillus and characterized by the formation of tubercles on the lungs and other tissues of the body, often developing long after the initial infection. 2.Tuberculosis of the lungs, characterized by the coughing up ...
Drugs & Devices Business support Nanoconsult is in close cooperation with the business unit: Translational Biomedical Engineering of the Fraunhofer ITEM (Institute for Toxicology and Experimental Medicine) mdXperts based in Wernigerode, Germany and Dublin, Ireland is a regulatory consultancy providing anal...
ceived no or less than 1 month of anti-tuberculosis treat- ment, the previously treated case is defined as a patient who has been treated for 1 month or longer using anti- tuberculosis medication, and the all case was defined as an MDR-TB case regardless of the treatment history [5]. ...