In addressing the key principles on treatment of multidrug-resistant tuberculosis(MDR-TB),it would be very appropriate to start with the preventive measures.Directly observed treatment, short-course(DOTS) is the most cost-effective strategy to curtail the development of drug resistance in Mycobacterium...
(MDR-TB).Results: Patients with sensitive pulmonary NDTB who are carriers of the wild alleles experienced the bacterioexcretion termination more frequently with the 60th dose (by 18,40%; (蠂 = 3,59, p = 0,052)); in MDR-TB the negative sputum microscopy was recorded more frequently with...
Treatment of MDR-TB infections is a major clinical challenge that has few viable or effective solutions; therefore patients face a poor prognosis and years of treatment. This review focuses on emerging drug classes that have the potential for treating MDR-TB and highlights their particular strength...
Drug clofazimine is a part of regimen for the treatment of MDR TB under the National TB Elimination Programme (NTEP). According to NPPA, there were references received from national advocacy group on shortage of clofazimine, which falls under the scheduled drug list. “Matter regarding shortage or...
new mdr tb test is a breakthrough - experts The rifamycins, long considered a mainstay of TB treatment, were a tremendous breakthrough when they were developed in the 1960's. While the rifamycins... M Ngcobo 被引量: 0发表: 0年 ...
“Although 90 percent of TB patients are cured with a long-term treatment for at least six months, irregular drug use can cause relapse or treatment failure and lead to MDR-TB or XDR-TB that are more difficult to treat,” Shim noted. ...
Novel technologies currently used for cancer therapy which could facilitate in-depth understanding of host genetics and the microbiome in patients with MDR-TB are discussed. Against this background, personalised cell-based HDTs for adjunct MDR-TB treatment to improve clinical outcomes are proposed as...
drug-resistant (XDR)-TB is a more dangerous strain than MDR-TB. The treatment of XDR-TB is more difficult, as patients are resistant to many of the second-line drugs. Highly potent antibiotics, such as thioridazine, have severe side effects and are used for the treatment of XDR-TB [8]...
“Z S -MDR-TB” versus “Z R -MDR-TB”: Improving Treatment of MDR-TB by Identifying Pyrazinamide Susceptibility. Emerg Microbes Infect. 2012; 1 :e5.Zhang, Y., Chiu Chang, K., Leung, C., Wai Yew, W., Gicquel, B., Fallows, D., et al. (2012) "ZS-MDR-TB" versus "ZR-MDR...
Electrocardiographic (ECG) monitoring is recommended for some of the new and re-purposed drugs used in the treatment of multidrug-resistant tuberculosis (MDR-TB), as these drugs have been shown to prolong the QTc interval. ECG monitoring is relatively new in the management of TB patients, and...