The brain colonizing counterpart of the parental cells primarily metastasizes to the brain, which is called the MDA-MB-231Br cell line. We have also shown that keratin 18 (an epithelial marker) plays a crucial role in the brain metastasis process as the MDA-MB-231Br cells have lower ...
MDA-MB-231-Br是MDA-MB-231的脑转移亚株。哪位老师手里有这个细胞株呀，能不能借一点？购买也可以...
通过上调乳腺癌细胞MDA-MB-231、SK-BR-3中NRP-1的表达,观察NRP-1对细胞增殖、凋亡、迁移及侵袭能力的影响。 方法 构建pcDNA3.1-NRP-1表达载体,脂质体介导NRP-1表达质粒转染MDA-MB-231、SK-BR-3细胞,用G418筛选出稳定转染的乳腺癌细胞株。利用RT-qPCR、Western blot法分别检测NRP-1基因mRNA及其蛋白表达;CCK...
摘要: 目的 通过上调乳腺癌细胞MDA-MB-231、SK-BR-3中NRP-1的表达,观察NRP-1对细胞增殖、凋亡、迁移及侵袭能力的影响.方法 构建pcDNA3.1-NRP-1表达载体,脂质体介导NRP-1表达质粒转染MDA-MB-231、SK-BR-3细胞,用G418筛选出稳定转染的乳腺癌细胞株.利用RT-qPCR、We... 查看全部>> ...
目的:探讨TM4SF1在人乳腺癌细胞MCF-7和MDA-MB-231中的表达情况以及靶向抑制TM4SF1基因后2种细胞的增殖、迁移能力的变化。方法:采用RT-PCR检测MCF-7和MDA-MB-231细胞中TM4SF1 mRNA表达情况,以正常乳腺上皮细胞MCF-10A的TM4SF1 mRNA表达作为参照; 应用TM4SF1 siRNA瞬时转染MCF
The isolated compounds (1–14) were tested for cytotoxicity against MDA-MB-231 cells, where compound 1, i.e., N,N-dimethyl-anthranilic acid, exhibited the most significant cytotoxicity against MDA-MB-231 cells, with an IC50 value of 90.28 ± 4.23 μM and apoptotic cell death ...
Vinorelbine delivery and efficacy in the MDA-MB-231BR preclinical model of brain metastases of breast cancer. Samala R,Thorsheim HR,Goda S,et al. Pharmacological Research . 2016Samala R, Thorsheim HR, Goda S, et al. Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of...
An J, Wang L, Zhao Y, Hao Q, Zhang Y, Zhang J, Yang C, Liu L, Wang W, Fang D, Lu T, Gao Y (2017) Effects of FSTL1 on cell proliferation in breast cancer cell line MDAMB231 and its brain metastatic variant MDAMB231BR. Oncol Rep 38(5):3001- 3010. https://doi.org/...
Vinorelbine delivery and efficacy in the MDA-MB-231BR preclinical model of brain metastases of breast cancer. Pharm Res. 2016;33:2904-19.Samala R, Thorsheim HR, Goda S, et al. Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer[J]....
A vibrational in vitro approach to evaluate the potential of monoolein nanoparticles as isofuranodiene carrier in MDA-MB 231 breast cancer cell line: new insights from Infrared and Raman microspectroscopiesValentina Notarstefano aMichela Pisani b...