LZY3016 showed potent antitumor activity in an MDA-MB-231 xenograft mouse model, suggesting LZY3016 is an up-and-coming antitumor candidate. The theoretical binding mode between LZY3016 and Hsp90 was obtained by molecular dynamics simulation.Zhenyu Li...
Three‐dimensional MR mapping of angiogenesis with α5β1(αvβ3)‐targeted theranostic nanoparticles in the MDA‐MB‐435 xenograft mouse model 来自 Wiley 喜欢 0 阅读量: 16 作者:AH Schmieder,SD Caruthers,H Zhang,TA Williams,JD Robertson,SA Wickline,GM Lanza ...
Andes-1537 treatment in an MDA-MB-231 xenograft mouse model In order to validate the use of Andes-1537 as a therapeutic tool against breast cancer, we studied the effectiveness of in vivo ASncmtRNA knockdown on tumor cell proliferation, in a xenograft assay in mice. Of the three cell lines...
WNT signaling enhances breast cancer cell motility and blockade of the WNT pathway by sFRP1 suppresses MDA-MB-231 xenograft growth. Breast Cancer Res. 2009;11(3):R32.Matsude Y. WNT signaling enhances breast cancer cell motility and blockade of the WNT pathway by sFRP-1 suppresses MDA-MB-...
(JNK), p38 and ERK5 in response to receptor tyrosine kinases and GTPases. We used MDA-MB-231 cells because of their ability to metastasize from the breast fat pad to distant lymph nodes for an orthotopic xenograft model to screen the function of seven MAP3Ks in controlling tumor growth ...
关键词:活体生物发光成像;MDA-MB-231细胞;三阴性乳腺癌;裸鼠;移植瘤模型中图分类号:R737.9 文献标志码:A 文章编号:1673-4254(2011)11-1812-07 EstablishmentofabioluminescentMDA-MB-231celllineforinvivoimagingofhuman triple-negativebreastcancerxenograft 阳4NGKe 1,XIESi-mei 1,HEJia叫un 1 ,RENYu 1,...
Additionally, the anticancer properties of 1-D-6-G were investigated in vivo using xenograft mice model. Finally, an in silico study was conducted to examine the interaction of 1-D-6-G and pathway-related proteins. MTT and colony formation assay results indicated that 1-D-6-G...
Oncology Dynamic contrast enhanced photoacoustic computed tomography in MDA-MB-231 and BT-474 xenograft tumor models PURDUE UNIVERSITY Keith M. Stantz ShafferMichael RichardsonPurpose: The objective of the research is to determine the feasibility of the prototype photoacoustic scanner to quantify localized...
The objective of this study is to perform a preclinical investigation of 64Cu-DOTA-atezolizumab in mice bearing MDA-MB231 (PD-L1-positive) xenograft. Methods: Atezolizumab was conjugated to DOTA and radiolabeled with 64Cu. The specific in vitro targeting efficacy of 64Cu-DOTA-atezolizumab was ...
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