Water mobility in cancer cells could be a powerful parameter to predict the progression or remission of tumors. In the present descriptive work, new insight into this concept was achieved by combining neutron scattering and thermal analyses. The results provide the first step to untangle the role ...
17-β-Estradiol Increases Expression of 52-kDa and 60-kDa SSA/Ro Autoantigens in Human Keratinocytes and Breast Cancer Cell Line MCF7 Wang D, Chan EK.: 17-beta-estradiol increases expression of 52-kDa and 60-kDa SS- A/Ro autoantigens in human keratinocytes and breast cancer cell ... ...
The MTT assay results of the tested compounds 3b and 3g on the MCF-7 cell line indicate that compound 3b con- taining 3-methoxy-donating function groups on chalcone moiety exhibited remarkable anticancer activity (~2.5 times more activity) compared to compound 3g containing an...
Redman and coworkers [26] investigated the effects of SeMet on four cell lines in vitro: MCF-7 breast carcinoma, UACC-375 melanoma, DU-145 prostate cancer, as well as normal diploid fibroblasts. This study investigated the IC50 of SeMet for for each cell line. SeMet concentrations ranged fr...
parameter sets (Supplementary Fig.11), and the definition of the good fit as those used for the simple model analysis. In subcluster 2, there were 5 out of 34 ERGs, 5 out of 48 IRGs, and 23 out of 60 DRGs that showed a good fit (Supplementary Fig.12). The good fit genes in ...
The cytotoxicity of compounds 1–18 and of cisplatin was tested on MCF-7 breast cancer cells. The cell line was selected as one of the most studied human breast cancer cell lines and cisplatin as a comparator, due to its widespread clinical use. The IC50 values are presented in Table 4 ...
Antitumor efficacy of DOX-incorporated micelles The antitumor efficacy was investigated with MCF-7 (drug- sensitive cancer cell line) and MCF-7/ADR (drug-resistant cancer cell line) xenografted BALB/c nude mice, respectively. MCF-7 cells and MCF-7/ADR cells were transplanted into female BALB/...
Using 3-nitrotyrosine as a parameter, we confirmed that the fish oil- supplemented diet significantly increases oxidative stress in tumor cells in vivo. Analysis of fatty acid content in plasma and tissues showed that feeding animals a 5% fish oil diet increases the levels of ...
Oral bioavailability (OB) is a key parameter to evaluate whether a drug can be developed, and it is also an effective indicator for evaluating the clinical efficacy of traditional Chinese medicine [12]. Drug likeness (DL) is currently widely employed as a crucial factor in assessing the ...
Supply Current Characteristics Num 1 2 3 4 5 6 7 8 9 10 11 12 13 C Parameter Symbol P T Run supply current FEI mode, all T modules on T 25.165 MHz 20 MHz 8 MHz 1 MHz RIDD C T Run supply current FEI mode, all T modules off T 25.165 MHz 20 MHz 8 MHz 1 MHz RIDD T Run ...