MCF-7 cells were chosen as the cell model in the present study given that the cell line is one of the most commonly used breast cancer cell line in breast cancer research [52]. Next generation sequencing (NGS) was employed to generate and compare the miRNA profiles of spheroid-enriched ...
We aimed to identify the key cancer-related processes that differ between the cell line analyses (MCF7-vs-MCF10A) and analysis of TCGA clinical samples (LumA-vs-normal), to understand the adequacy of cell lines as models for LumA BC. Unlike past methods which directly considered the differenc...
Clarke R, Lippman ME, Dickson RB, Spang-Thompsen M, Brünner N: In vivo/in vitro selection of hormone independent cells from the hormone dependent MCF-7 human breast cancer cell line. In: Immune-Deficient Animal in Experimental Medicine. Wu B, Zheng J (eds). Karger, Basel, 1989, pp ...
et al. Doxorubicin-loaded nanostructured lipid carriers functionalized with folic acid against MCF-7 breast cancer cell line. J Nanopart Res 25, 56 (2023). https://doi.org/10.1007/s11051-023-05704-7 Download citation Received09 November 2022 Accepted28 February 2023 Published18 March 2023 DOI...
The current study further investigates the cellular anticancer activities of an S. crispus subfraction (SCS) and its ability to modulate tamoxifen-induced effects on the breast cancer cell lines, MCF-7 and MDA-MB-231, as well as the non-cancerous breast epithelial cell line, MCF-10A....
Full size image Figure 6 Effect of Se-casein on apoptotic cell number. After 70 d on Se-casein treatment, the 4 largest MCF-7 tumors on each treatment were excised, embedded in wax, and sectioned at 5 μm onto microscope slides.The TUNEL assay was used to identify apoptotic cells and...
A, MCF7 cells were analyzed by fluorescence-activated cell sorting (FACS) using anti-CD44 and anti-CD24 antibodies. B, Quantification of the four subsets of MCF7 cells. C, Confirmation of the purity of the CD44+/CD24-/low cell type using flow cytometry. Full size image Detection of the...
The MCF-7 cell line was treated with either senescence-conditioned medium (SCM), IL-6 or IL-8 and then evaluated for phenotypic (CD44 and CD24 by FACS) and functional changes associated with an EMT program (migration/invasion) and for the acquisition of stem cell properties: mammosphere-for...
Acta Pharmacol Sin 2008 Mar; 29 (3): 385–396 Full-length article Modeling resistance index of taxoids to MCF-7 cell lines using ANN together with electrotopological state descriptors1 Pei-pei DONG2,3, Yan-yan ZHANG2,3, Guang-bo GE2,3, Chun-zhi AI2,3, Yong LIU2, Ling YANG2,5, ...
2.1. Intracellular Observation of QCDs-Labeled MCF-7 Cells Cancer MCF-7 cell line was incubated with various doses of QCDs, i.e., 50, 100, 200, 400 µg/mL for 24 h, and imaged (Figure 1). MCF-7 cells treated with 50 µg/mL of QCDs had full endo/lysosomes in perinuclear are...