基于药物MOA诱导的过敏小鼠模型选择之特应性皮炎 特应性皮炎(atopic dermatitis, AD)又称特应性湿疹,是一种易复发、瘙痒性的炎症性皮肤病,是皮肤科最常见的疾病之一,发病率高且难以根治。通常初发于婴儿期,儿童患病率高达20%,也可发于成人。疾病最主要的特征是皮肤干燥、反复发作的皮肤瘙痒及湿疹,使患者陷入“越...
Creative Bioarray provides the calcipotriol (MC903)-induced atopic dermatitis (AD) model, which has been widely used in research and can provide you with valuable insights into the efficacy of your compounds.
特应性皮炎(atopic dermatitis, AD)又称特应性湿疹,是一种易复发、瘙痒性的炎症性皮肤病,是皮肤科最常见的疾病之一,发病率高且难以根治。 首页>一站式服务>产品中心>疾病模型>自身免疫性疾病>皮肤系统>特应性皮炎 模型资源 AD模型 OXA诱导的AD模型
Atopic dermatitis is characterized by eczematous skin lesions and immunoglobulin E (IgE) hypersecretion. We investigated the role of JNK1 on the development of AD in mice. The vitamin D3 analogue MC903, a psoriasis therapeutic drug, was used to induce AD-like symptoms in wild-type (WT) and...
Role of group 2 innate lymphoid cells in mice with atopic dermatitis-like inflammatory response induced by MC903 Yang Ting, Zhang Kaoyuan, Li Zizhuo, Li Xu, Yu Bo, Dou Xia PDF 23 摘要/Abstract 摘要:【摘要】 目的 探讨2型固有淋巴样细胞(ILC2)在特应性皮炎(AD)中的作用。方法 以C57BL/6J和...
Characterization of MC903 induced Atopic Dermatitis﹍ike skin inflammation in micedoi:10.1096/fasebj.2020.34.s1.09550Katharine ChuZhi SuJoseph WetterMarian NamovicSteve McGaraughtyThe FASEB Journal
TSLP Produced by Keratinocytes Promotes Allergen Sensitization through Skin and Thereby Triggers Atopic March in Mice Atopic dermatitis often precedes the development of asthma, a phenomenon known as "atopic march". An important role of allergen sensitization developed thr... Juan,Manuel,Leyva-Castillo...
原名:Extracellular vesicles of commensal skin microbiota alleviate cutaneous inflammation in atopic dermatitis mouse model by reestablishing skin homeostasis 译名:共生皮肤微生物胞外囊泡通过重建皮肤稳态来减轻特应性皮炎小鼠模型中的皮肤炎症 期刊:Journal of Investigative Dermatology ...
Parnassin, a Novel Therapeutic Peptide, Alleviates Skin Lesions in a DNCB-Induced Atopic Dermatitis Mouse Model Atopic dermatitis (AD) is a chronic inflammatory skin disease which requires continuous treatment due to its relapsing nature. The current treatment includ... J Hwang-Bo,K Veerappan,H Mo...
The anti-inflammatory effect of topical TET on atopic dermatitis (AD) has not been reported. The purpose of this study was to explore the potential role of topical TET and its anti-inflammatory effects in a mouse model of AD.Methods: The 2% TET was applied topically to ears of MC903-...