Creative Bioarray provides the calcipotriol (MC903)-induced atopic dermatitis (AD) model, which has been widely used in research and can provide you with valuable insights into the efficacy of your compounds.
Atopic dermatitis is characterized by eczematous skin lesions and immunoglobulin E (IgE) hypersecretion. We investigated the role of JNK1 on the development of AD in mice. The vitamin D3 analogue MC903, a psoriasis therapeutic drug, was used to induce AD-like symptoms in wild-type (WT) and...
Characterization of MC903 induced Atopic Dermatitis﹍ike skin inflammation in micedoi:10.1096/fasebj.2020.34.s1.09550Katharine ChuZhi SuJoseph WetterMarian NamovicSteve McGaraughtyThe FASEB Journal
Role of group 2 innate lymphoid cells in mice with atopic dermatitis-like inflammatory response induced by MC903 Yang Ting, Zhang Kaoyuan, Li Zizhuo, Li Xu, Yu Bo, Dou Xia PDF 23 摘要/Abstract 摘要:【摘要】 目的 探讨2型固有淋巴样细胞(ILC2)在特应性皮炎(AD)中的作用。方法 以C57BL/6J和...
Molybdenum Nanoparticles Alleviate MC903-Induced Atopic Dermatitis-Like Symptoms in Mice by Modulating the ROS-Mediated NF-κB and Nrf2 /HO-1 Signaling Pat... Moreover, the ratio of Th2 cells in the skin and spleen was considerably decreased after BM administration in MC903-induced AD mice, ...
The purpose of this study was to explore the potential role of topical TET and its anti-inflammatory effects in a mouse model of AD.Methods: The 2% TET was applied topically to ears of MC903-induced AD-like BALB/c mice once a day. AD-like symptoms and severity were evaluated by ...
ATOPIC dermatitisINFLAMMATIONSKIN proteinsPATHOLOGICAL physiologyCHLOROQUINEIMMUNOGLOBULIN EThis paper aims to investigate the impact of CQ on type 2 inflammatory response in MC903-induced AD mice. Methods: An AD mouse model was established via MC903 induction. After CQ treatment, AD mice...
Molybdenum Nanoparticles Alleviate MC903-Induced Atopic Dermatitis-Like Symptoms in Mice by Modulating the ROS-Mediated NF-κB and Nrf2 /HO-1 Signaling Pathwaysdoi:10.2147/IJN.S472999Xiao, QinGuo, JingLu, YongzhouGao, JinJia, ChuanlongHuang, Minghuan...
? 2024 Japanese Society for Investigative DermatologyBackground: Although several mouse models of exogenous-agent–induced atopic dermatitis (AD) are currently available, the lack of certainty regarding their similarity with human AD has limited their scientific value. Thus, comprehensive evaluation of the...
摘要: Each exogenous-agent–induced AD model exhibited different characteristics.The MC903 model was the best to recapitulate most features of human AD among these exogenous-agent–induced AD models.The intestinal microbiota of all models showed significant differences after modeling....