Maternal inheritanceMitochondrial DNAMyotonic dystrophyBile acidsSeveral diseases with non-mendelian maternal inheritance patterns have been described, some of which appeared to be associated with abnormal mito
This pattern of inheritance is generally referred to as “uniparental inheritance,” and in this case, specifically it is called “maternal inheritance.” Some human mitochondrial diseases caused by mtDNA mutations are maternally inherited. Uniparental inheritance of mtDNA, as well as chloroplast DNA (...
Uniparental inheritance of mitochondrial DNA (mtDNA) is an evolutionary trait found in nearly all eukaryotes. In many species, including humans, the sperm mitochondria are introduced to the oocyte during fertilization1,2. The mechanisms hypothesized to prevent paternal mtDNA transmission include ubiquitinat...
which led to a rift between Khoisan and non-hunter-gatherer groups (i.e., Niger-Congo, Nilo-Saharan, Afro-Asiatic) by 160 kya, followed shortly by a split between Khoisan and RFHG groups 120–100 kya26,27. Mitochondrial studies have reinforced this pattern of Stone Age divergences...
The emerging challenge in the field is the identification of a role for mitochondrial genes in disorders that occur sporadically and without a clear pattern of maternal inheritance. A theoretical argument was advanced a decade ago that some disorders resulting from mtDNA mutations might appear sporadic...
1)maternal inheritance母系遗传 1.This review summarized some characteristics of mitochondrial diseases,and analysed the pattern ofmaternal inheritanceabout mitochondrial diseases.本文综述了线粒体病的特点,并对线粒体病的母系遗传方式进行了分析。 英文短句/例句 ...
(Fig.6I). Analysis of functional enrichment data of down-regulated genes withPATL2mutations at each stage showed that a variety of fundamental biological processes are involved: RNA splicing, mRNA processing and mitochondrial translation at the GV stage (FigureS3E); mRNA processing, chromosome ...
including mitochondrial related processes, for the genes that returned to single copy in all examined allopolyploids. The observed consistent bias towards the maternal subgenome donor, alongside the bias towards mitochondrial functions, suggests that observed subgenome dominance patterns in these allopolyploi...
The persistence of mtDNA to encode a small subset of mitochondrial proteins reflects the selective advantage of co-location of key respiratory chain subunit genes with their gene products. The disadvantage of this colocation is exposure of mtDNA to mutagenic ROS (reactive oxygen species), which are...
4) maternal inheritance 母系遗传 1. This review summarized some characteristics of mitochondrial diseases,and analysed the pattern of maternal inheritance about mitochondrial diseases. 本文综述了线粒体病的特点,并对线粒体病的母系遗传方式进行了分析。 更多例句>> ...