Throughout the airway, MC T cells are the predominant type in epithelium, while MC TC cells often reside near mucous glands and airway smooth muscle. In active atopics with asthma or rhinitis, increased numbers of MC T cells appear in the epithelium. This may account for the increased ...
Throughout the airway, MCT cells are the predominant type in epithelium, while MCTC cells often reside near mucous glands and airway smooth muscle. In active atopics with asthma or rhinitis, increased numbers of MCT cells appear in the epithelium. This may account for the increased numbers of ...
Mast Cell Mediators and AsthmaMast Cell Mediators and Asthmadoi:10.1378/chest.91.6_Supplement.171SMast cells are found beneath the basement membranes, near blood vessels in the submucosa, adjacent to submucous glands, scattered throughout the muscle bundles, in the interalveolar septa and in the br...
图书Bronchoalveolar Mast Cells and Asthma 介绍、书评、论坛及推荐
Asthma is a chronic inflammatory disease of the lung and its pathophysiology is initiated by mast cell activation in response to the antigen binding to IgE receptor as well as by TH2 cell activation. Mast cells are well established effector cells in asthma where they exacerbate the inflammatory ...
Many cells participate in the pathogenesis of asthmatic inflammation. The mast cell is localized at the interface of the internal and external environment ... CO Bingham,KF Austen - 《Journal of Allergy & Clinical Immunology》 被引量: 202发表: 2000年 IL-33 induces Th17-mediated airway inflammat...
During recent years, it has been suggested that mast cells may also have an important role in non-allergic chronic lung diseases, including chronic obstructive pulmonary disease (COPD) [2], asthma [3] and idiopathic pulmonary fibrosis (IPF) [4, 5]. There are two major subtypes of human ...
C. et al. Innate and adaptive T cells in asthmatic patients: relationship to severity and disease mechanisms. J. Allergy Clin. Immunol. 136, 323–333 (2015). Article CAS PubMed PubMed Central Google Scholar Aguilera-Lizarraga, J. et al. Local immune response to food antigens drives ...
Interestingly, the numbers of mast cells both in the epithelium (rs = -0.52, p < 0.05) and in the lamina propria (rs = -0.81, p < 0.001) were inversely correlated with the length of exposure to TDI before the onset of asthma. In conclusion, subjects who develop asthma after short-...
The role of the mast cell in asthma: a reassessment. Interest in the role of the mast cell in bronchial asthma has waxed and waned over several decades, but there is now compelling evidence that mast cells ma... Peter,Bradding - 《Current Opinion in Allergy & Clinical Immunology》 被引量...