Mast cell-nerve interactions in asthmaJPM van der KleijAletta KraneveldFrank RedegeldFP Nijkamp
and anaphylaxis. Triggers can be heat, cold, stress (physical or emotional), perfumes or odors, medications, insect stings, and foods. These symptoms are treated with medications including antihistamines, mast cell stabilizers, and leukotriene inhibitors, while anaphylaxis is a medical emergency requir...
Many cells participate in the pathogenesis of asthmatic inflammation. The mast cell is localized at the interface of the internal and external environment within the lung where it may respond to allergens and other exogenous stimuli. The activation of mast cells leads to the release of mediators ...
In asthma, mast cell activation can trigger degranulation, releasing secretory granule complex and preformed mediators, such as histamine and proteases, along with the synthesis of leukotrines and prostaglandins, and induction of cytokines and chemokines. Leukotrine inhibitors and omalizumab, which ...
Mast cell-nerve interactions in asthma 来自 Semantic Scholar 喜欢 0 阅读量: 66 作者: HPMVD Kleij 摘要: Asthma is characterized by a chronic inflammatory reaction in the airways. Roughly, asthma can be subdivided into atopic asthma involving elevated levels of serum IgE and a less familiar form...
This effect could be a combination of different mast cell proteases acting together [40], higher amounts of protease inhibitors and growth factors or that mast cells may promote the synthesis of anti-fibrotic growth factors, potentially making mast cells protective against remodeling processes in the...
Phytochemical studies observed presence of saponin, alkaloids, flavonoids, and glycosides. In conclusion EAPL possesses anti asthmatic potential. 展开 关键词: Abrus precatorius Asthma Mast cell Allergy DOI: 10.1016/S1995-7645(11)60030-8 被引量: 31 ...
Potent, Small-Molecule Inhibitors of Human Mast Cell Tryptase. Antiasthmatic Action of a Dipeptide-Based Transition-State Analogue Containing a Benzothiazo... Inhibitors of human mast cell tryptase (EC 3.4.21.59) have therapeutic potential for treating allergic or inflammatory disorders. We have inve...
Kaliner MA (1987) Mast cell mediators and asthma. Chest 91 [Suppl]:171–176KALINER M.Mast cell mediators and asthma. Chest 1985;87(suppl):2S- 4S.Kaliner, M. Mast cell mediators and asthma, chest,. 91,1715-65 (1987)Kaliner, M. (1985). Mast cell mediators and asthma. Chest 87S, ...
Pollen allergies, asthma, Mast Cell Activation Syndrome (MCAS) and/or Eosinophilic Esophagitis (EoE) can heighten during the Fall season and be a beast to manage. Near Lake City, Colorado I’ve written previously about Mast Cells and the Fall Flare on this blog, and I’ve learned some new...