In the general population, higher body mass index (BMI) is associated with increased all-cause mortality [1], with the nadir of the curve generally found in the upper normal-weight range [2], though the relationship is J-shaped [3], as also underweight carries an increased risk of death...
A growing body of evidence supports the comorbidity between depression (DEP) and obesity, yet the genetic mechanisms underlying this association remain unclear. Our study explored the shared genetic architecture and causal associations of DEP with BMI. W
Center for Computational and Integrative Biology and Department of Molecular Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Ramnik J. Xavier Contributions S.G. wrote the software and conducted experiments. G.H. adapted MAGMa substructure labelling for auxiliary model...
Arthritis and Tissue Degeneration, Hospital for Special Surgery, New York, NY, USA Cristina Rozo & Laura T. Donlin Department of Medicine, Division of Rheumatology, Allergy and Immunology, University of California, San Diego, La Jolla, CA, USA ...
/California Newswire/ — ComForCare Home Care North County San Diego, a leading provider of in-home care services, has partnered with OverSightMD Inc., the leader in employee & patient population oversight, to deliver daily employee and pa...
general health questionnaire HbA1c : glycated haemoglobin A1c HDL-C: high density lipoprotein cholesterol IL-6: interleukin 6 IPAQ: international physical activity questionnaire MetS: metabolic syndrome OR: odds ratio PAI-1: plasminogen activator inhibitor-1 ROC: receiver operating characterist...
Institute for Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital Campus, Crewe Road, Edinburgh, EH4 2XU, UK Matthieu Vermeren, Rodanthi Lyraki, Sachin Wani, Omar Albagha & Toby Hurd Rangos Research Center, Children’s Hospital of Pittsburgh, Pittsburgh, PA, 15224...
Methods: We identified 1,961 ancestrally diverse, genotyped individuals with documented exposure to a SGLT2i in the Mass General Brigham Biobank, a hospital-based biobank linked with patient medical records. Of these, 736 individuals had a baseline HbA1c ≥ 6% within 6 months of the index ...
Racial/ethnic disparities in the prevalence of diabetes and prediabetes by BMI: patient outcomes research to advance learning (PORTAL) multisite cohort of adults in the US. Diabetes Care. 2019;42(12):2211–9. Article PubMed PubMed Central Google Scholar Hernán MA, Robins JM. Using big ...
The four-part model adjusted for the positive expense skew (80%) with ambulatory and inpatient (hospital) utilization. Other approaches that adopted the RAND two-part estimation methods provided averages in lifetime expenditures.The proposed model modifies the two-part model to address estimation ...