Spatial omics technologies can reveal the molecular intricacy of the brain. While mass spectrometry imaging (MSI) provides spatial localization of compounds, comprehensive biochemical profiling at a brain-wide scale in three dimensions by MSI with single-cell resolution has not been achieved. We demonst...
The cortical and subcortical neural correlates underlying item and order information in verbal short-term memory (STM) were investigated by means of digit span in 29 patients with direct electrical stimulation during awake surgery for removal of a neoplastic lesion. Stimulation of left Broca's area ...
Comparison of the spatial and temporal information retrieved from near-infrared phase and average intensity (DC) data reveals that these data types can play a complementary role in the study of the temporal and spatial features of the optical response associated with brain activation during a finger...
Ideally, elucidating the role of specific brain circuits in animal behavior would require the ability to measure activity at all involved synapses, possibly with unrestricted field of view, thus even at those boutons deeply located into the brain. Here, we introduce and validate an efficient scheme...
Faradization of the Mind. Current Biology, 8, R8±R11.Walsh, V. (1998). Brain mapping: Faradization of the mind. Current Biology, 8, 8-11.Walsh V (1998). Brain mapping: Faradization of the mind. Current Biol 8:R8±R11.Walsh, V., Brain Mapping: Faradization of the Mind, Current...
Allodynia, a form of neuropathic pain, is defined as pain in response to a non-nociceptive stimulus. The brain regions responsible for pain, which are not normally activated, can be activated in allodynic mice by providing a suitable stimulus to Aβ-fibers, which transmit signals from tactile ...
T1 mappingT2 mappingfast imaginghuman brain imagingVariations in the intrinsic T(1) and T(2) relaxation times have been implicated in numerous neurologic ... SCL Deoni,TM Peters,BK Rutt - 《Magnetic Resonance in Medicine》 被引量: 559发表: 2005年 High-resolution T1 mapping of the brain at...
Polarised light imaging (PLI) utilises the birefringence of the myelin sheaths in order to visualise the orientation of nerve fibres in microtome sections of adult human post-mortem brains at ultra-high spatial resolution. The preparation of post-mortem brains for PLI involves fixation, freezing and...
A. in The Synaptic Organization of the Brain (ed. Shepherd, G. M.) 159–203 (Oxford Univ. Press, 1998). Miura, K., Mainen, Z. F. & Uchida, N. Odor representations in olfactory cortex: distributed rate coding and decorrelated population activity. Neuron 74, 1087–1098 (2012). CAS ...
The aim of the present study was to investigate the morphology of brain differences in white and gray matter structures in the compulsive phenotype of rats selected by SIP using high-resolution magnetic resonance imaging, in order to clarify the neuroanatomical substrates related to OCRDs. ...