Recently, studies on whole-exome sequencing (WES) of large cohorts of people with periventricular heterotopia (PVH) have reported an association with loss-of-function variants in the MAP1B gene. However, neurological phenotypes of these patients remain poorly characterized. Four family members with ...
其中MAP1B,又称为MAP5,是脑发育中主要微管蛋白,尤其在新生儿的脑中表达丰富。源于小鼠的抗MAP1B(NP_005900.2;GeneID 4131)单克隆IgG抗体(3G5),与微管蛋白(tubulin)和其它微管相关蛋白没有免疫反应。可以与小鼠、大鼠、人等交叉反应。 产品内容 抗体液(Reagent A)(200微克/毫升) 100微升 产品说明书 1份 保存...
Gene Name: MAP1B Protein Name: Microtubule-associated protein 1B (MAP-1B) [Cleaved into/ MAP1B heavy chain; MAP1 light chain LC1] Human Gene Id: 4131 Swiss-Prot: P46821 Formulation: Liquid in PBS containing 50% glycerol, and 002% sodium azide Source: Rabbit Purification: The antibody ...
Gene disruption or knockout studies of the MAP1B gene led to a delayed development of the nervous system in mice. It includes the N-terminal heavy chain and a C-terminal light chain. The MAP1B heavy chain has a microtubule-stabilization effect, and contains an actin-binding site that may...
Gene Name MAP1B Accession No. P46821 P14873 P15205 Description microtubule associated protein 1B(MAP1B) Homo sapiens This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an...
[3] "Entrez Gene:MAP1B microtubule-associated protein 1B". [3]Opal P,Garcia JJ,Propst F,Matilla A,Orr HT,Zoghbi HY(Sep 2003) "Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis".J.Biol.Chem.278(36):3469...
该MAP1B Polyclonal Antibody. This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that...
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor pol
(white) in lentivirus-infected cortical slices. Scale bars: 20 μm.cMAP1B intensity in mCherry+ neurons in human cortical slices. Two-tailed, unpaired Student’st-test,p = 0.0058.N = 3 individual cortices.dExperimental strategy for targeted activation of endogenousMAP1Bgene ...
IB(MAPIB)gene[J].JCenBtol1997;137(7):1615-1626. 12HanleyJG,KoulenP,BedfordF,Gordon-WeeksPR,Moss sJ.TheproteinM_AP1BlinksGABACreceptorstothe cytoskeletonatretinalsynapses【JJ.Ⅳature1999;397:66- 69.? 13GcoldRG,O~renR,Gordon-WeeksPR.Glycogensynthase ...