1.(Anatomy) any of the milk-producing glands in mammals. In higher mammals each gland consists of a network of tubes and cavities connected to the exterior by a nipple 2.(Zoology) any of the milk-producing glands in mammals. In higher mammals each gland consists of a network of tubes an...
Peter Greaves MBCHB FRCPATH, in Histopathology of Preclinical Toxicity Studies (Third edition), 2007 Publisher Summary The chapter studies the anatomy of the endocrine system and the non-neoplastic changes associated with mammary glands. A mammary gland is a sensitive indicator of the functional activi...
Macrophages serve multiple functions including immune regulation, morphogenesis, tissue homeostasis and healing reactions. The current paradigm holds that mammary gland macrophages first arise postnatally during the prepubertal period from the bone marrow-derived monocytes. Here we delineate the origins of ti...
Diffuse, non-specific fluorescence was observed using the CUBIC protocol in the absence of the primary antibodies (Additional file 1: Figure S1, top panel). Whole-mount histochemical and IHC analysis combined with CUBIC-based tissue clearing Excised and fixed mammary glands were immersed in reagent...
Mammary gland development in humans and mice takes place predominantly after birth. Structurally, mammary glands are constructed of ducts and lobules lined by hierarchical cells that range from stem cells to progenitors to terminally differentiated cells.4 Mammary stem cells (MaSCs), located at the ...
Milk is synthesized in mammary glands (MG) involving a large number of genes, the expression of which is modulated at a nutritional level [1] and by the health status [2]. Mastitis is the inflammatory response of the mammary gland to pathogens. This pathology is one of the most prevalent...
Fig. 1. Three-dimensional inspection of basal cell architecture in the mammary gland during the life cycle of a female mouse. Mammary glands from female mice on postnatal day 10 (pre-puberty), 6 weeks of age (puberty), adulthood (>8 weeks old), gestation (13.5 days post coitum), lactati...
Increased rates of proliferation may impact the cellular composition of the mammary gland by altering cell cycle dynamics leading to changes in the differentiation status of the cells. First, inguinal mammary glands from 8-week-old mice were assessed for luminal and myoepithelial markers cytokeratin ...
Elucidation of the bovine mammary gland transcriptome by RNA-seq is essential for identifying candidate genes that contribute to milk composition traits in dairy cattle. Results We used massive, parallel, high-throughput, RNA-seq to generate the bovine transcriptome from the mammary glands of four ...
To assess the KO efficiency, 2nd and 4th mammary glands were dissected from WTand a2V-KO mice. (b) Fold decrease in mRNA expression levels of a2V was assessed by real-time-PCR (RT-PCR). before fold-change calculation, the values were normalized to endogenous control glyceraldehyde 3-...