There is no predisposition for neoplasms to arise in any specific gland. The size of the tumor at the time of diagnosis is quite variable. As a rule larger tumors (>3 cm) are malignant, however, size of mammary tumors in cats does not correlate with biological behavior, even small ...
tumor stagingveterinary oncologyMammary gland neoplasms are predominant in dogs. However, sentinel lymph node (SLN) status assessment criteria have not been established for these cases. In this retrospective, secondary analysis, diagnostic case control study, CT images of 65 superficial inguinal SLNs ...
[16,17]. Two mediators of progesterone paracrine signaling have been defined in the mammary gland: the tumor necrosis factor (TNF) family member receptor activator for nuclear factor κB ligand (RANKL) and the int/Wingless (Wnt) ligand, Wnt4. Both RANKL and Wnt4 colocalize with PR-positive ...
et al. VEGF-B, VEGF-A, FLT-1, KDR, ERBB2, EGFR, GRB2, RAC1, CDH1 and HYAL-1 genes expression analysis in canine mammary gland tumors and the association with tumor clinicopathological parameters and dog breed assessment. Vet. Sci. 8, 212 (2021). Article PubMed PubMed Central Google...
This study aimed to evaluate the relationship between the molecular phenotype of the primary mammary tumor and its related lymph node metastasis in the dog to develop prognostic-predictive models and targeted therapeutic options. Twenty mammary tumor sam
Mammary gland tumors are the most common malignant diseases which seriously threaten the health of women and female dogs. There is a lack of an effective tumor marker which can effectively assist in the early diagnosis, and prognosis of mammary gland tumors in veterinary clinical medicine. IL-6,...
Global gene expression in canine mammary gland tumor cell lines. (A) Hierarchical clustering of MGT cell lines, MDCK and TP53 K/O fibroblast. (B) Heatmap plot of differentially expressed genes from the comparison of RNA-seq from Canine tumor cells with normal cells filtered by the fold change...
lymph node. This is due to the anatomy that caudal pairs of mammary gland have their lymphatic drainage into inguinal lymph node whereas cranial pairs into axillary lymph node. Epithelial tumor which might be metastasized through lymphatics to regional lymph node was evident. By convention most ...
mammary gland, invasion into the surrounding tissues, and metastases to the lymph nodes [25,34,35]. Another study demonstrated that the expression level of Ki-67 measured in metastases to lymph nodes had a positive correlation with its expression in the tumor tissue [36]. However, levels of ...
(CS, MC and SC). All the correlations show that the carcinomas with worse prognosis present shorter collagen fibres. Correlations of the mean collagen fibre length with other clinical and pathological data were performed, such as patient age, clinical staging, tumor size, lymph node status, ...