Tumors of the mammary glands of dogs are a complex and diverse group of neoplasms. Multiple primary tumors are frequently observed and often are of different histologic types; therefore, each individual tumor should be histopathologically evaluated, for biologic behavior is dependent on the most ...
Cell morphology and growth curve of canine mammary gland tumor cell lines. (A) Eight cell lines were observed under light microscopy (Scale bar = 100 μm). (B) The growth curve of MGT cell lines, the table below shows the doubling time calculated. Each value represents the means of 3...
Mammary gland tumor is the most common spontaneous tumor in intact female dogs, and its poor prognosis remains a clinical challenge. Ivermectin, a well-known anti-parasitic agent, has been implicated as a potential anticancer agent in various types of human cancer. However, there are no reports...
Mammary gland tumors are the most common malignant diseases which seriously threaten the health of women and female dogs. There is a lack of an effective tumor marker which can effectively assist in the early diagnosis, and prognosis of mammary gland tum
In this study, a hybrid spheroid model of canine mammary gland tumor (MGT) cell lines (CIPp and CIPm) and canine macrophages (DH82) was established. The effects of hypoxia induced by the spheroid culture system on the anti-cancer drug resistance of canine MGT cells were investigated. A ...
5.The Analysis of Metastatic Factors and Cell Line Characters on the Canine Mammary Gland Tumor;犬乳腺肿瘤转移关联因子及细胞系性状解析 6.Progress of circulating tumor cell (CTC) of breast cancer循环肿瘤细胞在乳腺癌中的研究现状 7.Study on the Correlation Between Molecular Expression and Biological ...
Mammary myoepithelial cells are important for normal mammogenesis and organostructural homeostasis, and have additionally been shown to have tumor suppressive properties (Gudjonsson et al., 2002; Jones et al., 2003; Polyak and Hu, 2005; Sánchez-Céspedes et al., 2016). Absence of ME cells ...
Here,to investigate DNA methylation changes in canine, we treated a canine mammary gland tumor cell line with a DNA methylation inhibitor, 5-aza-2'-deoxycytidine (5-aza). Cell growth was significantly retarded following 5-aza treatment and the epithelial marker genes CDH1 and KRT18 were ...
Barcus, C. E.et al.Elevated collagen-i augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells.Breast Cancer Res.19, 1–13 (2017). ArticleCASGoogle Scholar
8. Spontaneously occurring canine mammary gland tumors (CMT) have been proposed to have advantages as a model of human breast cancer compared to murine models, particularly when examining the tumor stroma9,10,11. In fact, recent work supports similarities between prognostic collagen signatures of ...