Leadley, P., and A. Baerga-Otiz. 2003. Mammalian fatty acid synthase: Closure on a textbook mechanism? Chem. Biol. 10:101-106.Leadlay P,Baerga-Ortiz A.Mammalian Fatty Acid synthase. Closure on a textbook mechanism. Chemistry and Biology . 2003...
刷刷题APP(shuashuati.com)是专业的大学生刷题搜题拍题答疑工具,刷刷题提供Mammalian fatty acid synthase has the enzyme activities ofA.hydrolaseB.ACPC.transferaseD.dehydrase的答案解析,刷刷题为用户提供专业的考试题库练习。一分钟将考试题Word文档/Excel文档/PDF
CC-115, a triazole-containing compound, is a dual mTOR/DNA-PK inhibitor currently in clinical trials. To further develop this compound, we sought to investigate factors that may affect cellular response to CC-115. Previously it has been shown that fatty acid synthase (FASN) up-regulates DNA-...
Fatty acid released from adipose tissue during starvation is the precursor of ketone bodies12 and mitochondria-localised 3-hydroxy-3-methylglutaryl-coenzyme A synthase 2 (HMGCS2) is a rate-limiting enzyme of ketogenesis. Though levels of β-OHB during starvation were lower in L-Atg5−/− mic...
3c). Many mitochondrial proteins (for example, cytochrome c, ATP synthase subunits, malate dehydrogenase and mitochondrial chaperone HSPA9) had H1/2 values that exceeded those reported in brain tissues (Supplementary Data 3). Fig. 3: Mouse ovaries have a >10-fold higher fraction of extremely ...
The measurement of respiratory chain enzyme activities and citrate synthase activity was performed as previously described32. Intraperitoneal glucose tolerance test Experiments were performed following 4 h of fasting starting at ~6:00. Blood glucose was monitored using the Contour ...
The second step of this pathway is catalyzed by the enzyme alkyl-dihydroxyacetone phosphate synthase, which exchanges an sn-1 fatty acid in ester linkage to dihydroxyacetone phosphate with a long chain fatty alcohol to form an alkyl ether intermediate. Once produced, ether lipids are precursors for...
Hydroxymethylglutaryl CoA synthase 2 (HMGCS2) encodes a mitochondrial protein that catalyses the first reaction of ketogenesis and controls the metabolic fate of fatty acids in the liver of starved animals (Vila-Brau et al., 2011). ACOT1 encodes an acyl-CoA thioesterase (CoASH) involved in ...
Two genes involved in nucleotide metabolism, CTP synthase and xanthine phosphoribosyltransferase were also up-regulated in the mutants derived from the passage of meat-borne Lb. sakei strain through the GIT of axenic mice [57]. Transporters and their importance in metabolic flexibility and regulation...
(BMECs) by upregulating the expression of ZO-1, Occludin and CD31. The phosphorylation of necessary protein kinase B (AKT) and glycogen synthase kinase 3β (GSK3β) increased after treatment with alisol A. To explore the root device, AKT ended up beingWestern Blot Analysisinhibited. Not ...