The human fatty acid synthase: a new ther- apeutic target for coxsackievirus B3-induced diseases? Antiviral Res 2007;76:150-8.Rassmann A, Henke A, Jarasch N, Lottspeich F, Saluz HP, Munder T. The human fatty acid synthase: a new therapeu- tic target for Coxsackievirus B3-induced ...
英文名字 Recombinant Human Fatty acid synthase (FASN), partial 供应商 Biomatik 产品货号 RPC25596 产品报价 ￥询价/20ug ￥询价/100ug ￥询价/1mg 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868 ...
Human fatty acid synthase (hFAS) is a complex, multifunctional enzyme that is solely responsible for the de novo synthesis of long chain fatty acids. hFAS is highly expressed in a number of cancers, with low expression observed in most normal tissues. Although normal tissues tend to obtain fa...
Snapshots of acyl carrier protein shuttling in human fatty acid synthase Article Open access 20 February 2025 Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor Article Open access 18 May 2020 Data availability The atomic coordinates of...
专利名称：REGULATION OF HUMAN S-ACYL FATTY ACID SYNTHASE THIOESTERASE-LIKE ENZYME 发明人：XIAO, YONGHONG,TOWLER, ERIC, M.申请号：EP0107297 申请日：20010626 公开号：WO0200855A3 公开日：20020606 专利内容由知识产权出版社提供 摘要：Reagents which regulate human S-acyl fatty acid synthase thioesterase-...
Fatty acid synthase (FASN) mRNA expression significantly decreased following Gimeracil exposure in both the presence and absence of FFAs (Table 1), with the most significant decrease observed for the highest dose of Gimeracil, (adjusted p-value 0.0123 and < 0.0001 for vehicle and FFA exposure...
This review documents the changing perspectives on the function of fatty-acid synthase and fatty-acid synthesis in human tumor biology. With the recent discovery that human cancer cells express high levels of fatty-acid synthase and undergo significant endogenous fatty-acid synthesis, our understanding...
The type I fatty acid synthase (FASN) is responsible for the de novo synthesis of palmitate. Chain length selection and release is performed by the C-terminal thioesterase domain (TE1). FASN expression is up-regulated in cancer, and its activity levels are controlled by gene dosage and ...
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FAS（fatty acid synthase）是一种多功能酶复合物，参与了细胞内脂肪酸的合成过程。FAS重组蛋白是通过基因重组技术合成的具有活性的FAS蛋白分子。其结构复杂，包括多个功能域，如ACP（acyl carrier protein）、KS（ketosynthase）等，每个功能域都参与了脂肪酸合成的不同步骤。FAS重组蛋白在生物学中有着多重功能。首先...