While bone marrow-derived plasma cell neoplasms (plasmacytoma/multiple myeloma) are the most common primary malignant bone tumor(s), osteosarcoma is the next most common malignant tumor that originates in bone, followed by chondrosarcoma. As in benign bone tumors, there can be significant overlap ...
cancer,malignant neoplastic disease- any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream myeloma- a tumor of the bone marrow (usually malignant) composed of cells normally found...
RATIONALE: Bone marrow (BM)-derived mesenchymal stem cells (MSCs) hold great promise for cardiovascular cell therapy owing to their multipotency and culture expandability. OBJECTIVE: The aim of the study was to investigate whether MSCs can treat experimental acute myocardial infarction (MI) and diabe...
Conditions for depletion of cells from bone marrow using monoclonal antibodies and immunomagnetic beads were studied. HA22T/VGH cells labeled with the supravital dye Hoechst 33342 were seeded into normal bone marrow at a ratio of cells to marrow cells of 1:9. The immunobeads used were M-450 ...
Among all children suffering from malignant disease brain tumors take the 2nd place: 12–24% after leukemia (31–42%). They are followed by lymphoma (7–13%), neuroblastoma and Wilm’s tumor (8–10% each), and tumors of the bones and the gastrointestinal tract (4–5% each)223, 281,...
Multiple myeloma (MM) is characterized by the clonal expansion of monoclonal immunoglobulin-secreting plasma cells within the bone marrow (BM). It has become clear that the intimate reciprocal relationship between the tumor cell clone and the niches of the BM microenvironment plays a pivotal pathophys...
Growth in semisolid agar of prostate cancer cells obtained from bone marrow aspirates. However, colony formation was most frequently seen when a radionuclide scan was positive at the aspiration site and when tumor cells were microscopically detectable by Wright staining of a smeared aspirate. The po...
a malignant bone tumor. Also calledosteogenic sarcoma. retinoblastoma a common childhood malignancy of the eye that develops from retinal cells. sarcoma a rare malignant tumor of the soft tissues that commonly develops in the lower extremities. ...
Innovative diagnosis and treatment methods based on nanoparticles (NPs) have emerged, offering new hope for the management of malignant bone tumors and potentially extending patient survival while improving quality of life. Firstly, NPs have made significant strides in the controlled release of tumor dr...
Clinical use of FDG PET/CT in (1) primary malignant bone tumors including osteosarcoma, malignant fibrous histiocytoma, and primary bone lymphoma, (2) hematopoietic tumors with bone marrow involvement, such as plasmacytoma, multiple myeloma, lymphoma and leukemia, and (3) benign tumors and tumor-...