Malignant hyperthermia is a genetic myopathy inherited by autosomal dominant pattern with variable penetrance. Masseter muscle spasm and many neurological conditions are associated with this condition. A susceptible person, when exposed to a triggering agent, may manifest MH syndrome. The triggering agent...
Malignant hyperthermia is a rare genetic condition in which a person experiences an adverse physiological reaction to the...
Malignant hyperthermia (MH), a potentially fatal hypermetabolic reaction, is a genetic disorder of skeletal muscle.1–8 The triggers for the hypermetabolic reaction are some anesthetics and muscle relaxants, or extreme stress in the form of heat or exercise.4–6 If recognized early, the MH ...
Malignant hyperthermia is a genetic myopathy inherited by autosomal dominant pattern with variable penetrance. Masseter muscle spasm and many neurological conditions are associated with this condition. A susceptible person, when exposed to a triggering agent, may manifest MH syndrome. The triggering agent...
Genetic screeningMutation—chromosome aberrationsMutation—missenseDihydropyridine receptorMyopathy–central coreThe rapid advances in DNA technology in recent years have been valuable in understanding the pharmacogenetic disease of malignant hyperthermia. Malignant hyperthermia is proving to be a more complex ...
美 英 网络恶性高热;恶性高温;恶性高热症 英英 网络释义 n. 1. araregeneticconditionofintensemusclecontractionthatproducesgreatheatandadangerouslyhightemperature.Itisbroughtonbyanaestheticdrugs.
Orphanet Journal of Rare Diseases (2015) 10:93 DOI 10.1186/s13023-015-0310-1 REVIEW Malignant hyperthermia: a review Henry Rosenberg1, Neil Pollock2, Anja Schiemann3, Terasa Bulger2 and Kathryn Stowell3* Open Access Abstract Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal ...
摘要: Malignant hyperthermia is a hereditary trait characterized by hypercatabolic reactions induced by anesthetic drugs, or physical or emotional stress. Patients must be treated quickly and efficiently in order to prevent irreversible organ damage and death.关键词: hyperthermia malignant ...
Genetic testing can be defined as an analysis or test that confirms the presence or the absence of a genetic condition; this does not necessarily involve the analysis of DNA as there are still many clearly genetic conditions where the gene has not yet been identified. In the context of MH,...
Malignant hyperthermiais a condition in which susceptible individuals may develop a potentially fatal state of severe generalized muscular rigidity,hyperpyrexia,metabolic acidosis, andmyoglobinuriawhen exposed to certain anesthetic agents or otherdrugs.217Susceptibility is usually transmitted as an autosomal ...