The 23 kDa thaumatin-like protein (TLP) from cherry was identified as a major allergen and designated Pru av 2. Its amino acid sequence contains a single potential N-glycosylation site. The glycosylation of Pru av 2 and its role in IgE-binding was investigated in this study. Natural (n)...
Sequence-specific 1H, 13C and 15N resonance assignments of the major cherry allergen Pru a 1. 来自 国家科技图书文献中心 喜欢 0 阅读量: 22 作者:P Neudecker,K Schweimer,J Nerkamp,M Boehm,P Rösch 摘要: Neudecker P, Schweimer K, Nerkamp J, Boehm M, Scheurer S, Vieths S, Sticht ...
C Inschlag,K Hoffmann-Sommergruber,G O’Riordain,H Ahorn,C Ebner,O Scheiner,H Breiteneder.Biochemical characterization of Pru a 2, a 23-kD thaumatin-like protein representing a potential major allergen in cherry (Prunus avium). International Archives of Allergy and Immunology . 1998Inschlag C...
Objective Pru p 3 is the major allergen of peach. T-cell epitopes of Pru p 3 have not been investigated among Chinese peach allergic patients yet. The objective of this study was to map the major T-cell epitopes of Pru p 3. Methods Peripheral blood mononuclear cells( PBMCs) from 20 pe...
Conformational epitope mapping of Pru du 6ꎬ a major allergen from almond nut[ J] . Mol Immunolꎬ 2013ꎬ 55(3) : 253-263.Willison LN, Zhang Q, Su M, Teuber SS, Sathe SK, et al. (2013) Conformational epitope mapping of Pru du 6, a major allergen from almond nut. Mol ...
The use of hypoallergenic derivatives is considered beneficial to promote the safety and efficacy of allergen-specific immunotherapy. We aimed to assess the efficacy of reduced and alkylated (R/A) Pru p 3, a hypoallergenic folding variant of the major peach allergen, in subcutaneous immunotherapy (...
By inducing class switching of B cells via IL-4 they are responsible for the production of allergen-specific IgE, the major effector molecule in this disease. In addition, they produce IL-13 and IL-5 thereby stimulat- ing airway epithelial cells and eosinophils9,10. Th2 cells also ...
In this study, the focus was onin silicoidentified 53 cassava PR-10 proteins, which can be categorized into two main subgroups: 34 major latex proteins (MLPs) and 13 major allergen proteins, Pru ar 1, based on their phylogenetic relationship. The genome collinearity analysis with the rubber ...
AllergenApricotENEAPeachPru ar 5Hev b 5Peach and apricot can cause allergic reactions with symptoms ranging from mild to very severe, including anaphylaxis. Sometimes subjects allergic to fruits of the Prunus genus have been reported to be also allergic to rubber latex products. The objective of ...
The influence of thermal processing and nonenymatic as well as polyphenoloxidase-catalyzed browning reaction on the allergenicity of the major cherry allergen Pru av 1 was investigated.After thermal treatment of the recombinant protein rPru av 1 in the absence or presence of carbohydrates,SDS-PAGE,...