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Magnetic nanoparticles are one of the most important and widely used types of nanomaterials, whose unique properties make them special compared to other nanostructures. These particles can be used in various fields. But their role in biomedicine, especially in the field of drug delivery, is signific...
Previously, nanoparticles have delivered drugs in blood circulation in a controlled manner and relied upon their predisposition to penetrate the blood–brain barrier. However, in order to increase the delivery efficiency and pharmacological effect, we need to design a better strategy. Herein, we show...
Diagnosis and Drug Delivery to the Brain Abhirup Mandal, ... Ashim K. Mitra, in Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices, 2017 6.4 Magnetic Nanoparticles Magnetic nanoparticles (MNPs) have gained interest in the field of drug delivery. These magnetic particles have...
Magnetic nanoparticles USPIO: Ultra-small superparamagnetic iron oxide MT: Magnetic targeting ADSCs: Human primary adipose-derived stem cells hMSCs: Human mesenchymal stem cells MSCs: Mesenchymal stromal cells NSCs: Neural stem cells ESCs: Embryonic stem cells ...
Nanoparticles enhance brain delivery of blood-brain barrier-impermeable probes for in vivo optical and magnetic resonance imaging. Proc Natl Acad Sci USA. 2011; 108 :18837–18842.Koffie RM, Farrar CT, Saidi LJ, William CM, Hyman BT, Spires-Jones TL. Nanoparticles enhanc...
Nanoparticles (NPs) with modification of brain-targeting molecules have been extensively exploited for therapeutic gene delivery across the blood–brain ba... Sai,An,Yuyang,... - 《Biomaterials》 被引量: 40发表: 2013年 Neuroprotective potential of cerium oxide nanoparticles for focal cerebral ischemic...
A biocompatible, efficacious therapeutic that easily crosses the blood-brain barrier (BBB) is needed to treat neuronal toxicity observed in HIV-infected individuals. Magnetic nanoparticles (MNPs) have successfully delivered anti-HIV agents across in vitro BBB transwell model. However, MNPs at high dos...
(MDDSs) based on magnetic nanoparticles (MNPs) are attracting increasing attention owing to their favorable biocompatibility and excellent multifunctional loading capability. MDDSs primarily have a solid core of superparamagnetic maghemite (γ-Fe2O3) or magnetite (Fe3O4) nanoparticles ranging in size ...
Because magnetic and iron oxide nanoparticles are so diverse and can be used in multiple applications such as imaging or therapy, they have attractive features for brain delivery. However, the greatest limitations for the use of MRI/MPI for imaging and treatment are in brain delivery, with one ...