AKT INHIBITORS FOR TREATING CANCER EXPRESSING A MAGI3 - AKT3 FUSION GENEThe present invention provides methods of treating cancer.doi:WO2012177925 A1MEYERSON, MatthewBANERJI, ShantanuGETZ, GadCIBULSKIS, KristianLAWRENCE, MichaelMIRANDA, Alfredo, Hidalgo...
Membrane-associated guanylate kinase WW and PDZ domain containing 3 (MAGI3); protein kinase B|[gamma]| (PKBG; AKT3)Patient sample and cell culture studies suggest AKT (PKB; PKBA; AKT1) inhibitors could help treat breast cancers expressing the MAGI3-AKT3 fusion protein. Further details on ...