IFN-gamma enhances bovine macrophage responsiveness to Mycobacterium bovis: Impact on bacterial replication, cytokine release and macrophage apoptosis. Immunol Cell Biol 2005; 83: 643-50.M. Denis,D. N. Wedlock,B. M. Buddle.IFN-γ enhances bovine macrophage responsiveness to Mycobacterium bovis: ...
Besides the established role of interleukin-12 (IL-12) and IL-18 on interferon-gamma (IFN-gamma) production by natural killer (NK), T, and B cells, the effects of these cytokines on macrophages are largely unknown. Here, we investigated the role of IL-12/IL-18 on nitric oxide (NO) ...
MACROPHAGE CANDIDACIDAL ACTIVITY IN HUMAN NEONATES: DECREASED SENSNIVITY TO MODULATION BY IFN-|[gamma]|In an attempt to understand the mechanisms of host defense in the term neonate against candida, we studied interaction between Calbicans and monocyte-derived macrophages (MDM) cultured for 5 days...
IFN-gamma and TNF regulate macrophage expression of the chemotactic S100 protein S100A8. The murine calcium-binding protein S100A8 is a potent chemoattractant for neutrophils and monocytes in vivo and in vitro but may also play a protective rol... K Xu,CL Geczy - 《Journal of Immunology》 被...
IFN-gamma Primes Macrophage Activation by Increasing Phosphatase and Tensin Homolog via Downregulation of miR-3473b IFN-γ primes macrophage activation by increasing Phosphatase and Tensin homolog via Downregulation of miR-3473b. J Immunol. 2014;193:3036-44... Yiquan,Xue,Qiuyan,... - 《Journal of...
1A murine macrophage cell line, J774, expressed nitric oxide (NO) synthase activity in response to interferon-gamma (IFN-, 10 u ml1) plus lipopolysaccharid... J Assreuy,FQ Cunha,FY Liew,... - 《Br J Pharmacol》 被引量: 780发表: 1993年 IL-15 is a novel growth factor for murine ...
adaptive immunityIFNgammainnate immunitymacrophageIFN‐γ plays a critical role in the immune response to bacterial infections. It is established that IFN‐γ is mainly produced by NK/ILC1 cells and T cells, and most of papers have rejected the biologic reality of alternative sources for more tha...
Ray JC,Wang J,Chan J,et al.The timing of TNF and IFN-gammasignaling affects macrophage activation strategies duringMycobacterium tuberculosisinfection. Journal of Theoretical Biology . 2008Ray JCJ, Wang J, Chan J, Kirschner DE. The timing of tnf and ifn-gamma signaling affects macrophage ...
TNF-alpha and IFN-gamma stimulate a macrophage precursor cell line to kill Listeria monocytogenes in a nitric oxide-independent manner. TNF-α and IFN-γ stimulate a macrophage precursor cell line to kill Listeria monocytogenes in a nitric oxide-independent manner. J Immunol. 1994; 153 ... PJ...
IFN-gamma rapidly primes the macrophage via JAK1/2-STAT1 pathway so that it can subsequently undergo a slower classical type 1 activation upon exposure to T helper (Th)1 cytokines such as IFNgamma or other activators, including tumor necrosis factor and lipopolysaccharide, e.g. in intracellular...