This study prompted a number of other investigators to look for oxidative activity in patients with lung fibrosis. 这个研究结果促使许多学者去探索肺纤维化患者体内的氧化活性。 dictsearch.appspot.com 2. Diffuse lung fibrosis and silicotic nodule formation are a basic pathological change in silicosis. ...
Diffuse interstitial pulmonary fibrosis Pulmonology A group of disorders characterized by scarring of deep lung tissue, leading to SOB and loss of functional alveoli, limiting O2 exchange; ILD is more common in smokers Etiology Inorganic and organic dusts, gases, fumes, vapors, medications, radiation...
Mice are the most common species used when studying pulmonary fibrosis. However, several animal models of lung fibrosis exist; ranging from mice to primates. Bleomycin is a commonly used chemotherapeutic agent that causes an acute lung injury response followed by lung fibrosis. Other approaches includ...
Idiopathic pulmonary fibrosis, which affects about 100,000 people in the US each year and leads to death within three years of diagnosis, has only one therapy in the US: lung transplantation.NEWSEducation
网络特发性肺纤维化 网络释义 1. 特发性肺纤维化 【摘要】:特发性肺纤维化(idiopathic lung fibrosis)是一种原因不明的慢性进行性肺成纤维细胞增生性疾病,新近研究发现其发 … cdmd.cnki.com.cn|基于 1 个网页
Lung fibrosis is characterized by the continuous accumulation of extracellular matrix (ECM) proteins produced by apoptosis-resistant (myo)fibroblasts. Lung epithelial injury promotes the recruitment and activation of fibroblasts, which are necessary for tissue repair and restoration of homeostasis. However,...
Lung fibrosis is a severe disease characterized by epithelial cell injury, inflammation and collagen deposition. The metalloproteases meprinα and meprinβ have been shown to enhance collagen maturation and inflammatory cell infiltration via cleavage of
Lung fibrosis (LF) is a chronic progressive, incurable, and debilitating condition of the lung, which is associated with different lung disease. Treatment options are still sparse. Nintedanib, an oral tyrosine kinase inhibitor, significantly slows the LF
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fibrosis in the lung is like a healing wound on skin, Noble said. The fibrotic cells clamp down, pull in the skin, and hold it together more tightly. In the lungs, this clamping down of small airways prevents essential respiration and leads to death due to irreversible loss of lung ...