High ferritin and low transferrin saturation are associated with pre-diabetes among a national representative sample of US adults. Clin Nutr. December 28, 2012. [Epub ahead of print.]Cheung CL, Cheung TT, Lam KS, Cheung BM. High ferritin and low transferrin saturation are associated with pre-...
The relative increase in malaria risk for children with high iron status was statistically significant only among those with a concurrently normal serum soluble transferrin receptor concentration (<8.3 mg/L; IRR: 1.97; 95% CI: 1.20, 7.37).Conclusions: Iron adequacy in 4- to 8-y-old children ...
transferrin saturationwomenSerum iron and total iron binding capacity (TIBC) were determined in a population sample of 1462 women in age strata between 38 and 60. Serum iron and TIBC values were similar in the various ages studied but with a slight trend towards higher serum iron and lower ...
When in circulation, iron forms a complex with transferrin, which binds the transferrin receptor protein-1 (TFRC) on the cell membrane to be taken up by the cell [42]. Excess iron can be stored as ferritin or exported from the cell. Ferroptosis can be triggered when there is an excess ...
Iron is essential for tumor cell growth. Previous studies have demonstrated that apart from transferrin-bound iron uptake, mammalian cells also possess a transport system capable of efficiently obtaining iron from small molecular weight iron chelates (Sturrock et al., 1990). In the present study,...
proteins with a suggested role in non-transferrin iron transportacross plasma membrane was detected [18].The existence oftransport system for iron uptake from low-molecular-masscomplexes including ferric citrate was well documented [19–23].However,specific molecules involved in the transportsystem ...
Analysis was performed for hemoglobin and serum levels of ferritin, transferrin, iron, and transferrin saturation. During the visit at 7 years of age, a psychometric intelligence quotient (IQ) was assessed using the validated Wechsler Intelligence Scale for Children—fourth edition (WISC-IV), ...
Methods: 207 severely anemic children were assessed for levels of hepcidin, ferritin, serum transferrin receptor, erythropoietin, hematological indices, C-reactive protein, interleukin-6, malaria parasites and HIV infection. Deficiency of bone marrow iron stores was graded and erythroblast iron ...
Regular blood transfusion, a definite treatment for anemia caused by premature hemolysis and ineffective erythropoiesis, double-burdened these patients and contributed to elevated iron storage and trafficking, reflected in high ferritin and serum iron levels.Citation5 Concurrently, transferrin becomes ...
14 Prior studies in preterm infants have shown that RBC transfusions increase proinflammatory cytokine levels15,16 and non–transferrin-bound iron but not oxidant stress,17 although none of the aforementioned studies has evaluated the effect of blood donor characteristics. Understanding the effects of ...