Inadequate production of red blood cells can happen when the bone marrow itself is depressed, such as in HIV12 or some malignancies; because there are hormonal imbalances, such as with chronic inflammation;13 or due to increased demand (such as during pregnancy), nutrient malabsorption or ...
For most of the low-burden TP53 mutations, we observed that the mutation burden increased during relapse after chemo- and/or immunotherapy, but persisting and diminishing mutations were also recorded, mainly among mutations <1% VAF. According to our observation, the risk of an expanding TP53 ...
2017, the prevalence of wasting was modeled using the observed number of children in cluster d, who were found to be wasted as a binomial count data Cd among a sample size Nd. $$\begin{array}{l}C_d|p_{i\left( d \right),t\left( d \right)},N_d \sim {\mathrm{Binomial}}\...
Blood samples were obtained prior to surgery. Peripheral blood mononuclear cells (PBMC) were isolated from patients’ heparinized venous blood by Ficoll-Amidotrizoate (provided by the LUMC pharmacy) gradient centrifugation. Tumor material and respective normal colorectal samples were obtained immediately af...
We used several parameters, CD, chemo cell ratio (CCR) and chemo index (CI) to evaluate the chemotactic function of neutrophils more comprehensively. It was difficult to isolate enough LDNs from the peripheral blood of healthy controls to complete chemotactic experiments. The chemotactic ability of...
Exclusive breastfeeding (EBF)—giving infants only breast-milk for the first 6 months of life—is a component of optimal breastfeeding practices effective in preventing child morbidity and mortality. EBF practices are known to vary by population and c
Furthermore, premature infants appear to be unresponsive to the blood gas changes occurring during apnea; thus they seem to behave like highland residents with impaired chemoreceptor activity. These observa- tions suggested that low birth weight infants might have chemoreceptor activity similar to that...
and underwent enzymatic digestion using a Tumour Dissociation kit (Miltenyi Biotec) and gentle MACS Dissociator (Miltenyi Biotec) to obtain single-cell suspension. After centrifugation at 300 × g, both tumour-derived cells and ascites underwent red blood cell removal using Red Blood Cell Lysis...
Chemoimmunotherapy Reduces the Progression of Multiple Myeloma in a Mouse Model. Cancer Prev. Res. 2010, 3, 1265–1276. [Google Scholar] [CrossRef] [Green Version] Zhong, H.; Lai, Y.; Zhang, R.; Daoud, A.; Feng, Q.; Zhou, J.; Shang, J. Low Dose Cyclophosphamide Modulates Tumor...
Blood-brain barrier, cytotoxic chemotherapies and glioblastoma. Expert Rev. Neurother. 2016, 16, 1285–1300. [Google Scholar] [CrossRef] Zhang, D.Y.; Dmello, C.; Chen, L.; Arrieta, V.A.; Gonzalez-Buendia, E.; Kane, J.R.; Magnusson, L.P.; Baran, A.; James, C.D.; H...