The protein analysis of myelin and direct determinations of myelin basic protein revealed very low amounts of this component in sciatic nerves from mutants. The other peripheral nervous system myelin proteins and the myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase were not affected. ...
In myelin deficient mutant mice peripheral nerves appeared normally myelinated and the myelin sheath showed the typical alternation of minor and major dense lines. The protein analysis of myelin and direct determinations of myelin basic protein revealed very low amounts of this component in sciatic ...
Crystal Structure of HLA-DR2 (DRA*0101, DRB1*1501) Complexed with a Peptide from Human Myelin Basic Protein Susceptibility to multiple sclerosis is associated with the human histocompatibility leukocyte antigen (HLA)-DR2 (DRB1*1501) haplotype. The structure of HL... KJ Smith,J Pyrdol,L Gauth...
Brain co-localization of miR-21/LacZ with specific neural markers was examined by double immunofluorescence in reporter mice, while extent of immunostaining for myelin basic protein and PDGFR伪 was determined in miR-21 knockout and wild-type mice. Levels of miR-21, and mRNAs of selected miR-...
Deibler GE, Martenson RE, Kies MW (1972) Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species. Prep Biochem 2: 139–165 Google Scholar Karlsson B and Alling C (1982) Radioimmunoassay of myelin basic protein. A methodological evaluation. J Imm...
Finally, in the in vivo model of experimental allergic encephalomyelitis, anti-B7.2 mAb treatment abrogated protection offered against disease by low-dose myelin basic protein feeding, while anti-B7.1 had no effect. Anti B7.2 had no effect on disease suppression by high-dose oral Ag. These ...
Myelin basic protein References Madangarli N, Bonsack F, Dasari R, Sukumari-Ramesh S. Intracerebral hemorrhage: blood components and neurotoxicity. Brain Sci. 2019. https://doi.org/10.3390/brainsci9110316. Article PubMed PubMed Central Google Scholar Shao A, Zhu Z, Li L, Zhang S, Zhang...
Abbreviations: BBB, blood-brain barrier; HI, hypoxic ischemia; IOD, inte- grated optical density; LPS, lipopolysaccharide; MBP, myelin basic protein; NS, normal saline; VLBW, very-low-birth-weight; WM, white matter 41 42 WANG ET AL. MATERIALS AND METHODS A neonatal rat model of cerebral ...
SDS-CZE allowed us to determine simultaneously the CSF minor low MW proteins other than βTP, such as β2-microglobulin, ψ-trace protein, myelin basic protein, etc., while the CIEF electropherograms suggested that βTP were separated into several fractions with the different PI values. These...
crosslinking by radiolabeling well-known RNA targets, myelin basic protein and early growth response gene-2 (EGR-2)43 and incubating with vector control, QKI and QKI-RAF1 proteins expressed in HEK293 (Supplementary Figure 4a). Compared with vector control, QKI bound to both RNA targets but ...