In a prospective, double-blind randomized trial the efficacy and safety of low molecular weight heparin and un fractionated heparin were compared for the prevention of post operative deep vein thrombosis in patients undergoing major surgery for breast and pelvic cancer. Three hundred fifty-eight ...
Objective To compare the clinical efficacy and influence on blood coagulation between low molecular weight heparin( LMWH) and unfractionated heparin( UFH) in the adjuvant treatment of elderly patients with severe pneumonia( SP). Methods 105 elderly SP cases were randomly divided into the LMWH group ...
COMPARING THE EFFECT OF COMMERCIAL HEPARIN WITH LOW-MOLECULAR-WEIGHT HEPARIN ON PARTIAL PROTHROMBIN TIME IN HEMODIALYSIS PATIENTS Background: Low-molecular-weight heparins (LMWH) are an important new class of antihrombotic agents. They differ from Un-fractionated haparin (UFH) in having relatively ...
A further aspect of the invention provides a method of assaying a sample chosen from heparin, low-molecular-weight heparin, ultra low molecular weight heparin, and oligosaccharides, wherein the sample is analyzed using a reversed phase column coated with a quaternary ammonium salt for chromatographic...
Heparinised venous blood was collected either immediately prior to or six days after commencement of dietary challenge and peripheral blood mononuclear cells (PBMC) isolated by Ficoll-Hypaque density centrifugation (Anderson et al., 2000) from each blood sample. The PBMC cells were resuspended in ...
A number of LWMP fragments, composed of highly cationic peptides with molecular weights ranging from 700 to 1900 d, were prepared by digestion of native protamine with the protease thermolysin. These fragments were fractionated using a heparin affinity chromatography, and their relative binding ...
Functional Heterogeneity of Antiheparin-Platelet Factor 4 Antibodies: Implications in the Pathogenesis of the HIT Syndrome With the affinity purification, two major components, peaks I and II, with high antiheparin-platelet factor 4 antibody titers were eluted. The purity of all the fractionated immun...
73 Combinations of SU5416 treatment with fractionated radio-therapy or continuous low MW heparin in glioblastomadoi:10.1016/S0167-8140(01)81095-1NoneELSEVIERRadiotherapy & Oncology
thrombin inhibition;LMWH;antithrombin;heparin oligosaccharides;ternary complex 1. Introduction Low Molecular Weight Heparins (LMWH) are lifesaving anticoagulant drugs which have been used for several decades in the prevention and treatment of venous and arterial thromboembolism [1]. LMWH are industrially ...
The low molecular weight fractions F-I and F-II from the sulfated galactan of Botryocladia occidentalis exhibited high anticoagulant activities, and the total thrombin inhibition mediated by heparin cofactor II was even stronger than the parent polysaccharide [18]. The low-molecular-weight fractions ...