Reductions in IGF-1 levels in CF contribute to the impaired alveolar macrophage function. Exposure to IGF-1 ex vivo results in improved function of CF alveolar macrophages. Further studies are needed to determine whether alveolar macrophage function can be enhanced in vivo with IGF-1 treatment....
The aim of the present study was to investigate the effect of low-normal and high-normal levels of IGF-1 in growth hormone (GH) deficient adults on cognition and wellbeing during GH treatment. A randomized, open-label, clinical trial including 32 subjects receiving GH therapy for at least ...
LF-rTMS was applied to the inferior frontal gyrus (IGF) for patients with nonfluent aphasia and to the superior temporal gyrus (STG) for patients with fluent aphasia. Results: On pretreatment fMRI, the most activated areas were in the left hemisphere (n = 16) and right hemisphere (n = 8...
Common methods for improving vascularization include employment of gene-modified cells expressing angiogenic factors and scaffolds releasing angiogenic factors like VEGF and IGF1 [7, 8]. A promising, non-invasive, indirect technique to improve vascularisation is a low intensity shockwave treatment (Li-...
Fluoride Treatment Increased Serum IGF-1, Bone Turnover, and Bone Mass, but Not Bone Strength, in Rabbits We hypothesized that fluoride partly acts by changing the levels of circulating calcium-regulating hormones and skeletal growth factors. The effects of ora... CH Turner,LP Garetto,AJ Dunipa...
IGF-1; Uricacid; Cardiovascularrisk AbstractBackgroundandaims:Lowinsulin-likegrowthfactor-1(IGF-1)levelsandhighuric acidconcentrationsareassociatedwithcardio-metabolicdisorders.AcuteIGF-1infusionde- creasesuricacidconcentrationinhealthyindividuals.Inthisstudy,weaimedtoexaminethe relationshipbetweenIGF-1anduricacid...
Mcan IGF, lcvcls are simificanllv increased 48 h following thc first injection o f G H and IGFI icvcls arc normal after2 months. N o correlation was found bclwccn Lhc plasma lcvcls o l G H B P and lGFl nor belwecn their increment undcr G H treatment. I n conclusion, low GHBP...
Low-level laser irradiation affects the release of basic fibroblast growth factor (bFGF), insulin-like growth factor-I (IGF-I), and receptor of IGF-I (IGFBP3) from osteoblasts Saygun I, Nizam N, Ural AU et al (2012) Low-level laser irradiation affects the release of basic fibroblast gro...
A detailed understanding of how the GH and IGF-I regulate muscle growth, especially in early vertebrates, is still lacking. The fine flounder is a flatfish species exhibiting remarkably slow growth, representing an intriguing model for elucidating growth regulatory mechanisms. Key components of the GH...
Females in the low dose treatment arm were found to have a better working memory and a better strategic memory control after 24 weeks as opposed to the females in the high treatment arm. With respect to mood, the decrease in IGF-1 levels in females within the low treatment arm was ...