cancerpathologyimmunohistochemistrytreatmentsurgerychemotherapyLow-grade serous carcinoma is a rare tumor accounting for approximately 5% of ovarian carcinomas. It usually originates in a stepwise fashion from a serous borderline tumor. Its association with BRCA mutations is uncommon; however, it can be ...
LGSOC, low-grade serous ovarian cancer; HGSOC, high-grade serous ovarian cancer; STIC, serous tubal intraepithelial carcinoma. adapted from [3], [4], [6], [7], [18] Recently, the grading system has changed from a three level of nuclear differentiation into low-grade cancers (mild or ...
Low-grade serous carcinoma of the ovary or peritoneum.doi:10.1093/annonc/mdw085chemotherapyhormonaltherapylow-gradeserouscarcinomaovariancancertargetedagentsOver the past decade, the strategy for clinical trial design in making progress against epithelial cancers of the ovary/peritoneum/fallopian tube has ...
低级别浆液性卵巢癌(Low-grade serous ovarian cancer,简称LGSOC)是一种卵巢癌比较少见的亚型,癌细胞的生长速度较慢,细胞异型程度较低。相对于高级别浆液性卵巢癌(High-grade serous ovarian cancer),LGSOC的病情发展通常较缓慢,但复发风险很高,大约85%的患者会遭遇复发,而且会对化疗耐药。
Low-grade serous ovarian cancer was previously thought to be a subtype of high-grade serous ovarian cancer, but it is now recognized as a distinct disease with unique clinical and molecular behaviors. The disease may arise de novo or develop from a serous borderline ovarian tumor. Although it ...
Updated findings from RAMP 201 show that avutometinib/defactinib is generally well tolerated among those with low-grade serous ovarian cancer. "These updated results confirm the potential of this new combination therapy to change practice and be the new standard for care for recurrent low-grade ...
The FDA granted an orphan drug designation to avutometinib either alone or in combination with defactinib for recurrent low-grade serous ovarian cancer.
ovarian cancer, low grade serous carcinoma, macropapillary serous carcinoma, micropapillary serous carcinoma, serous borderline tumor, atypical proliferative serous tumorInvasive micropapillary serous carcinoma (MPSC) also designated “low-grade serous carcinoma” (LGSC) of the ovary is characterized by ...
Background: Ovarian cancer (OCa) is the deadliest of all gynecologic cancers in the United States. About 10% of all cases of serous ovarian cancer have the unusual histology named low-grade serous carcinomas (LGSOC), that has a distinct clinical behavior with a unique molecular landscape. LG...
Hormonal Maintenance Therapy for Women With Low-Grade Serous Cancer of the Ovary or Peritoneum. 来自 国家科技图书文献中心 喜欢 0 阅读量: 53 作者: Gershenson, David M., Bodurka, Diane C., Coleman, Robert L., Lu, Karen H., Malpica, Anais, Sun, Charlotte C. 展开 摘要: PurposeThe ...