近日,一组来自意大利的研究团队在杂志Sciencetranslationalmedicine上发表了一篇题为“Genomic instability analysis in DNA from Papanicolaoutestprovides proof-of-principle early diagnosis of high-grade serous ovarian cancer”的文章。本研究的目的是为pDNA中体细胞拷贝数改变(SCNAs)的分析提供实验证据,并将其纳入命名...
Serous tubal intraepithelial carcinoma (STIC) is a precancerous lesion of highgrade serous ovarian carcinoma (HGSOC). Usually, it arises from the fimbrial end of the tube, and it is associated with metastatic potential. On average, the time to progress from STIC to HGSOC i...
海外直订Tumor Microenvironment High Grade Serous Ovarian Cancer 高级别级别浆液卵巢癌的肿瘤环境科普读物 683元 (包邮,需用券)价格:783元满600减20每300减40淘金币可抵3%满1600减50满300减5满1000减30海外直订The Tumor Microenvironment of High Grade Serous Ovarian Cancer 高级别浆液性卵巢癌的肿瘤微环境20...
High-grade serous carcinomaOvarian cancerPrecursor lesionsCell of originTumorigenesisKnowledge of the molecular/genetic alterations and of the natural history of the cancer precursors that precede high-grade serous carcinoma continues to evolve. Comprehensive examination of the fallopian tubes removed from ...
Recent studies have suggested that the most common and lethal type of 'ovarian' cancer, i.e. high-grade serous carcinoma (HGSC), usually arises from epithelium on the fallopian tube fimbriae, and not from the ovarian surface epithelium. We have developed Ovgp1-iCreER T2 mice in which the ...
低级别浆液性卵巢癌(Low-grade serous ovarian cancer,简称LGSOC)是一种卵巢癌比较少见的亚型,癌细胞的生长速度较慢,细胞异型程度较低。相对于高级别浆液性卵巢癌(High-grade serous ovarian cancer),LGSOC的病情发展通常较缓慢,但复发风险很高,大约85%的患者会遭遇复发,而且会对化疗耐药。
A clinically applicable molecular classification for high- grade serous ovarian cancer based on hormone receptor expression. Sci Rep. 2016; 6: 25408. doi: 10.1038/ srep25408.Feng Z, Wen H, Bi R, Ju X, Chen X, Yang W, Wu X: A clinically applicable molecular classification for high- grade...
Many high-grade serous carcinomas (HGSCs) of the pelvis are thought to originate in the distal portion of the fallopian tube. Serous tubal intra-epithelial carcinoma (STIC) lesions are the putative precursor to HGSC and identifiable in ~ 50% of advanc
High-grade serous carcinoma (HGSC) is the most prevalent and aggressive subtype of ovarian cancer. The large degree of clinical heterogeneity within HGSC has justified deviations from the traditional one-size-fits-all clinical management approach. However, the majority of HGSC patients still relapse ...
The clinicopathological parameters such as residual tumor, grade, the International Federation of Gynecology and Obstetrics (FIGO) score are often used to predict the survival of ovarian cancer patients, but the 5-year survival of high grade serous ovarian cancer (HGSOC) still remains around 30%....