Low-grade gliomas are a heterogeneous group of tumors that overall have a better prognosis than WHO grade III and IV tumors. However, these tumors can devastate a child because of progression in proximity to critical structures, or the long-term consequences of therapy. Observation after complete...
low-grade glioma. In doing so we discuss the specific molecular drivers of pediatric low grade glioma and how to effectively test for them, review the newest therapeutic agents and their utility in treating this disease, and propose a risk-based stratification system that considers both clinical a...
low-grade glioma. In doing so we discuss the specific molecular drivers of pediatric low grade glioma and how to effectively test for them, review the newest therapeutic agents and their utility in treating this disease, and propose a risk-based stratification system that considers both clinical a...
Purpose: Immunohistochemical techniques were used to detect the expression of Ki-67, a nuclear proliferation marker, in 180 low-grade glioma tumor specimens to determine whether Ki-67 is a prognostic predictor of survival or tumor recurrence. Methods and Materials: A clinical database of 180 low-...
Low-grade glioma is the most common brain tumor in children. If eligible for surgery, overall survival rate for these children is 95 percent. However, for patients with tumors in locations that prevent surgical removal or whose tumor is progressive after surgery, prognosis is worse. ...
Significant advancements in neurosurgical planning, approach, and practice over the past five decades have improved the surgical management of diffuse low and high-grade gliomas. We sought to evaluate the extent to which LGG survival outcomes have evolved over the past fifty years using glioma ...
with deep learning network to predict the prognosis (high vs low-risk glioma), and thus accurately stratified gliomas patients21. However, these studies were in term of all types of gliomas instead of the sole LGGs. Until now, the analysis integrating multi-omics data to predict prognosis of...
To assess the activity and tolerability of temozolomide in children with progressive low-grade gliomas (LGGs). The authors reviewed the records of 13 children (6 months to 19 years old) with progressive LGGs and magnetic resonance imaging evidence of unresectable tumors who were treated with temoz...
low grade glioma - University of Louisville:低级别胶质瘤-路易斯威尔大学.ppt,neurocognitive decline prospective study of 26 patients treated for low-grade brain tumors 46-56 gy in 1.8-2 gy fractions excluded patients with pre-existing vascular disease di
Warmuth-Metz M, Herna´ iz Driever P, Soerensen N, Kortmann RD, Pietsch T, Faldum A (2012) Long-term follow-up of the multicenter, multidisciplinary treatment study HIT-LGG-1996 for low-grade glioma in children and adolescents of the German Speaking Society of Pediatric Oncology and Hema...