(2015). Loss-of-function analysis reveals distinct requirements of the translation initiation factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila spermatogenesis. PLoS ONE 10, e0122519.S. Ghosh and P. Lasko, "Loss-of-function analysis reveals distinct requirements of the translation ...
EphA tyrosine kinases are thought to act as topographically specific receptors in the well-characterized projection map from the retina to the tectum. Here, we describe a loss-of-function analysis of EphA receptors in retinotectal mapping. Expressing patches of a cytoplasmically truncated EphA3 rec...
qPCR analysis suggested the involvement of F1F0-ATPase 总之,我们克隆了并且描绘了β-AR基因五zebrafish orthologs代表三β-AR子型的同源染色体。 损失offunction分析显露了一个重要角色为zebrafish adrb2a在染色的章程,一致与哺乳动物的β2-AR。 qPCR分析在染色的dysregulation建议了F1F0腺苷三磷酸酶的介入以下所说...
In this study, we carried out a loss-of-function analysis of myosin thick filaments via gene-specific knockdown or using a myosin ATPase inhibitor BTS (N-benzyl-p-toluene sulphonamide) in zebrafish embryos. We demonstrated that knockdown of myosin heavy chain 1 (myhc1) resulted in sarcomeric...
doi:10.1038/s41598-017-06366-xKumar, Runjun DBose, RonScientific ReportsScientific ReportsKumar, R. D. & Bose, R. Analysis of somatic mutations across the kinome reveals loss-of-function mutations in multiple cancer types. Scientific Reports 7, 6418 (2017)....
Loss-of-function and gain-of-function mutations of calcium-sensing receptor: functional analysis and the effect of allosteric modulators NPS R-568 and NPS ... Loss-of-function and gain-of-function mutations of calcium-sensing receptor: functional analysis and the effect of allosteric modulators ...
First analysis of synaptic plasticity in MeCP2 null mice. Belichenko PV, Dahlstrom A (1995). Studies on the 3-dimensional architecture of dendritic spines and varicosities in human cortex by confocal laser scanning microscopy and Lucifer yellow microinjections. J Neurosci Methods 57: 55–61. B...
Functional analysis showed that these classes of mutations all resulted in increased translation of the main HR physiological ORF. Our results establish the link between MUHH and U2HR, show that fine-tuning of HR protein levels is important in control of hair growth, and identify a potential ...
Comparative sequence analysis of the complete set of 40S ribosomal proteins in the Senegalese sole (Solea senegalensis Kaup) and Atlantic halibut (Hippoglo... p pBackground/p pRibosomal proteins (RPs) are key components of ribosomes, the cellular organelle responsible for protein biosynthesis in ...
Molecular Characterization and Loss-of-Function Analysis of an Arabidopsis thaliana Gene Encoding a Phospholipid-Specific InositPhosphoinositides are important molecules that serve as second messengers and bind to a complex array of proteins modulating their subcellular location and activity. The enzymes ...