The article offers advice to a 55-year-old marathon runner experiencing leg weakness and whose magnetic resonance imaging (MRI) test revealed a loss of fluid in his lowest spinal disc. The runner is seeking a ...
Primary-progressive MS (PPMS) is characterized by a linear worsening of symptoms from disease onset [7] and given that the blood–brain barrier (BBB) is mostly intact, CNS/cerebrospinal fluid -localized mechanisms likely facilitate demyelination [8, 9]. Relapsing–remitting MS (RRMS) is ...
In this study, an interesting case of TBM who was initially treated as pyogenic meningitis in another center, was reported. Due to the progression of the illness and new symptoms, the patient was referred to our center where his diagnosis was confirmed with TBM with relevant investigations Tuberc...
et al. Pharmacokinetics of intrathecally applied BDNF and effects on spinal motoneurons. Exp. Neurol. 141, 225–239 (1996). Article CAS PubMed Google Scholar Croll, S. D. et al. Co-infusion with a TrkB-Fc receptor body carrier enhances BDNF distribution in the adult rat brain. Exp. ...
id after spinal tap 4390018 Method for preventing loss of spinal fluid after spinal tap4390018 Method for preventing loss of spinal fluid after spinal tapdoi:10.1016/0306-4522(83)90254-3None
3.2%of American youth with hearing loss had suffered meningitis Hearing loss caused by meningitis An infection in the lining and fluid around the brain and spinal column, meningitis can be viral, bacterial, fungal, or parasitic. While it doesn’t always result in hearing loss, people who ha...
The contribution of the inwardly rectifying K+ channel subtype Kir4.1 has been focused mainly on astrocytes, where they play important roles in the maintenance of resting membrane potential, extracellular K+ uptake, and facilitation of glutamate uptake i
MOG-positive disease is often found to present with “severe imaging lesions and mild clinical symptoms”. Regarding possible mechanisms, MRI in 70% of patients with this lesion shows significant swelling and enhancement of the spinal cord, without necrotic lesions [16]. For some MOG antibody-posi...
We recently uncovered an association between spinal osteoarthritis and height loss that was independent of incident vertebral fracture. However, the optimal cut-off value of historical height loss (HHL) for discriminating spinal osteoarthritis has not be
These mice show neurodegeneration, but also manifest symptoms that are not commonly linked to AD. For example, expression of MAPT driven by the mouse prion promoter results in accumulation of tau in the spinal cord leading to motor deficiencies15,22. Recently, groups have used the Tet-Off ...