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Loop is a new open source 3D geological and geophysical modelling platform in full development. The new platform consists of 4 main work packages: Knowledge Management: use of AI techniques for knowledge extraction from literature, maps and reports using geological ontology. Geological rules will be...
3D Model from the Hamersley region, Western Australia Install Option 1: Install with Anaconda This is the simplest and recommended installation process, with: conda install -c loop3d -c conda-forge map2loop Option 2: Install with pip
3d,e). Thus, SOSS–INTAC prevents the accumulation of paused Pol II and limits chromatin accessibility. R-loops affect SOSS–INTAC localization Owing in part to the higher thermodynamic stability of an RNA–DNA duplex compared with dsDNA, R-loops can accumulate at actively transcribed genomic ...
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(insulator model). We therefore examine the 3,736 loop pixels anchored on all 992 DMRs previously defined in human GM12878 cells57(colored dots in Fig.5c). Only three loci,H19,MESTandMRPL28, have DMR and AS loops, consistent with the idea that the ‘insulator model’ is not a ...
(Fig. 1.15). The stem–loop structures, also calledhairpins, play an important role in the tertiary folding ofRNAmolecules. They also serve as critical sites for the interaction with othernucleic acidsand proteins. One extensively studied example of secondary structures is the cloverleaf model of...
We systematically investigated the effect of each model extension with our analytical theory and fast 1D simulations, since 3D polymer simulations would be prohibitively slow. The setup for the 1D simulations mirrored 3D polymer simulations (Supplementary Fig.4a), and we recorded a successful synapsis...
given3Dmodelbyminimizingtheapproximationerrorbetweenthefittingsurfaceandtheoriginalmodel Theapproximationerrorisdefinedastheintegraloftheminimumdistancebetweeneachsurfelontheorigi nalmodelandthefittingsurface BycomparingthisalgorithmwiththeLoopsubdivisionwaveletdecomposi tionalgorithm,itisshownthatouralgorithmgeneratesbetterre...