Gastroesophageal reflux disease (GERD) is one of the most common disorders of the gastrointestinal tract. Clinical presentation can vary from simple heartburn to erosive esophagitis. Some patients require long-term, possibly life-long, therapy. The cost of treatment is substantial, as patients with ...
Proton pump inhibitors (PPIs) are central in the management of GERD and are unchallenged with regards to their efficacy. They are considered safe and more effective than histamine receptor antagonists for healing esophagitis and for preventing its recurrence using a long term maintenance treatment. ...
PPIs have better characteristics for the long-term treatment of GERD, because they have a long-lasting, strong effect of raising intragastric pH and have... Y Kinoshita,K Adachi,H Fujishiro - 《Journal of Gastroenterology》 被引量: 28发表: 2003年 GERD: Diagnosing and treating the burn Althoug...
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Short-term safety and efficacy of TIF (EsophyX, EndoGastric Solutions) were demonstrated inprevious trialswith up to 12 months of follow-up. In the current study, Trad and colleagues evaluated the durability of these outcomes at 36...
A comprehensive evaluation of the risks and 1-year burdens of gastrointestinal disorders in the post-acute phase of COVID-19 is needed but is not yet available. Here we use the US Department of Veterans Affairs national health care databases to build a c
Treatment of gastroesophageal reflux disease in adults: an individualized approach. Until the 1990s, most therapeutic trials in gastroesophageal reflux disease (GERD) focussed upon endoscopic lesions. In fact the correlation between patien... JP Galmiche,K Stephenson - 《Digestive Diseases》 被引量: 39...
摘要: Background: Omeprazole is effective in the treatment of reflux oesophagitis, and it is important to determine the lower dose limit with still appropriate clinical efficacy.关键词: Drug therapy omeprazole randomized controlled trial recurrence reflux oesophagitis ...
The authors suggest that GERD treatment be made common practice to reduce ring recurrence in patients with GERD. Five of the 30 patients without GERD were lost to follow-up, but 8 of the remaining 25 patients had recurrence after a mean follow-up period of 40.6 ± 12.2 months: ...
Long-term low-dose (≤325 mg) aspirin therapy is not, however, without the potential for adverse effects. In addition to increasing the risk of major gastrointestinal (GI) or cerebral bleeding,9 low-dose aspirin therapy is associated with a significant increase in the risk of GI adverse event...