V. Long-term effects of ketamine: evidence for a persisting impairment of source memory in recreational users. Drug and Alcohol Dependence . 2004; 75 (3):301–308. doi: 10.1016/j.drugalcdep.2004.03.006. [ Cross Ref ]Morgan CJ, Riccelli M, Maitland CH, Curran HV (2004b) Long-term ...
The acute antisuicidal effects of single-dose intravenous ketamine and intranasal esketamine in individuals with major depression and bipolar disorders: A systematic review and meta-analysis. J. Psychiatr. Res. 2021, 134, 57–68. [Google Scholar] [CrossRef] Fedgchin, M.; Trivedi, M.; Daly,...
Some side effects of ketamine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects....
Ketamine acts as a rapid clinical antidepressant at 25 min after injection with effects sustained for 7 days. As dissociative effects emerging acutely after injection are not entirely discernible from therapeutic action, we aimed to dissect the differences between short-term and long-term response ...
Long-term effects of a double hit murine model for schizophrenia on parvalbumin expressing cells and plasticity-related molecules in the thalamic reticular nucleus and the habenula Patrycja Klimczak, Julia Alcaide, Yaiza Gramuntell, Esther Castillo-Gómez, Emilio Varea, Marta Perez-Rando & ...
The goal of this pilot study was to evaluate the number of patients who complete the initial six-infusion acute-phase treatment and to identify the populat... FG Mathers,Levine,Arns 被引量: 0发表: 2018年 Is There Evidence for Long-Term Neurocognitive Effects of Sedatives? Ketamine anesthesia...
clinical drug development, you must know the processes in the brain that are involved. This is the first research that gives us an explanation for how ketamine produces long-term effects involving synaptic plasticity in thebrainand why ketamine has cumulative antidepressant effects—a huge step ...
Cerebellum was found to be down-regulated in both mice and humans after long-term of ketamine administration and it was caused by the apoptosis of Purkinje cells. Deleterious effects in other organs reported in long-term ketamine users include of kidney dysfunction leading to proteinuria, fibrosis ...
Uncovering Ketamine’s Mechanisms “This study is exciting, because it lays the groundwork for development of non-toxic treatments that exert antidepressant effects within hours like ketamine but that also have the longer-term sustained effects necessary for the treatment of depression,” said senior ...
Ketamine is frequently used to induce analgesia or anesthesia in laboratory animals, but its effects on learning and memory are poorly characterized. Long-term potentiation (LTP) is considered a cellular mechanism for learning and memory. Ketamine administration immediately abolishes hippocampal LTP in vi...