To date there are no genetic models to study the long-term effects of suppression of IKr and IKs in a model in which these channels control cardiac repolarization and the shape of its action potential. Other non-murine laboratory animal species that may be more suitable for in vivo ...
Long-term Silencing of Intersectin-1s in Mouse Lungs by Repeated Delivery of a Specific siRNA via Cationic Liposomes. Evaluation of Knockdown Effects by Electron Microscopy Published: June 21, 2013doi:10.3791/50316 Cristina Bardita*1,Dan Predescu*1,2,Sanda Predescu1,2...
Large-scale energy storage systems are essential for the integration of intermittent renewable energies, such as wind, solar and tidal power1,2. Benefiting from their nonflammability and abundant resources, aqueous sodium-ion batteries (ASIBs) are regarded as promising candidates for grid energy stora...
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The simple term “protective film” as used herein means a polarizer protective film like the protective film 30, and is different from the surface protective film to be temporarily used at the time of the production. The polarizer 10 is long, and the polarizing film laminate 100 is typically...
The above results show that the TAP coating effectively releases Ag+ into the surrounding environment to prevent bacterial infection, and shows antibacterial activity before the planktonic bacteria attach to the implant surface in the short and long term, respectively. However, the implant placement can...
These skin substitutes displayed good biocompatibility and can effectively avoid the accumulation of wound exudate and promote wound healing. However, it is still challenge to make a high efficient wound dressing with long-term antibacterial property and rapid wound healing rate [6,7]. The ...
of peri-implant infection and complex bacteria from peri-implantitis patients. More importantly, its antibacterial efficacy can persist for a long term (e.g., 12~16 weeks) in vitro, in animal model, and even in human oral cavity, which generally covers the whole formation process of osseo...
The term “effective amount” refers to that amount of a compound that is sufficient to effect treatment, as defined below, when administered to a mammal in need of such treatment. The effective amount will vary depending upon the specific activity of the therapeutic agent being used, the sever...
As used herein, the term “dental erosion” is defined as loss, softening, and/or demineralization of mammalian tooth substance (i.e., demineralization of enamel of the tooth typically with dissolution of such enamel). Preferably, such loss of tooth substance occurs by direct action of acid on...