, and systemiccorticosteroids), metabolic disorders, illicit drug use, abuse or misuse of prescription drugs such asCNS stimulants,diabetes mellitustreated with oral hypoglycemics or insulin, treatment with anorectic drugs, and excessive use of alcohol,benzodiazepines, sedative/hypnotics, or opiates....
The most common diagnosis at the initiation of treatment (ie, first prescription) among long-term (>90 days) and short-term (≤90 days) IR hydrocodone/acetaminophen users was back/neck pain, which was more common for long- versus short-term users (36.6% vs 14.1%, respectively) (Table 2...
Drugs of abuse, including alcohol, ablate the expression of specific forms of long-term synaptic depression (LTD) at glutamatergic synapses in dorsal striatum (DS), a brain region involved in goal-directed and habitual behaviors. This loss of LTD is asso
Long- or short-acting opioids for chronic non-malignant pain? A qualitative systematic review. Acta Anaesthesiol Scand. 2014;58:390–401. Article CAS PubMed Google Scholar Chou R, Turner JA, Devine EB, Hansen RN, Sullivan SD, Blazina I, et al. The effectiveness and risks of long-term ...
acting injectable antiretroviral therapy or LAI ART for short. Lessons learned from the longer-standing use of LAIs in the fields of mental health and addiction treatment hold particular relevance given that they treat a population that includes people with HIV (PWH). Moreover, conditions from the...
Related to its empirical dosing and short duration of action, frequent monitoring of the patient is required so that the effects of opioid toxicity, namely respiratory depression, do not return to wreak havoc. Nalmefene is a pure opioid antagonist structurally similar to naltrexone that can serve ...
Figure 1. Schematic representation of normal lung development, common triggers of preterm birth, key cellular and molecular pathways involved in preterm birth- and smoke/nicotine exposure-related short- and long-term pulmonary outcomes. Although infants born extremely preterm, i.e., during the late...